@article{c6e836a4a65e4e8abd346c02b993705d,
title = "Risk stratification and management of women with cardiomyopathy/heart failure planning pregnancy or presenting during/after pregnancy: a position statement from the Heart Failure Association of the European Society of Cardiology Study Group on Peripartum Cardiomyopathy",
abstract = "This position paper focusses on the pathophysiology, diagnosis and management of women diagnosed with a cardiomyopathy, or at risk of heart failure (HF), who are planning to conceive or present with (de novo or previously unknown) HF during or after pregnancy. This includes the heterogeneous group of heart muscle diseases such as hypertrophic, dilated, arrhythmogenic right ventricular and non-classified cardiomyopathies, left ventricular non-compaction, peripartum cardiomyopathy, Takotsubo syndrome, adult congenital heart disease with HF, and patients with right HF. Also, patients with a history of chemo-/radiotherapy for cancer or haematological malignancies need specific pre-, during and post-pregnancy assessment and counselling. We summarize the current knowledge about pathophysiological mechanisms, including gene mutations, clinical presentation, diagnosis, and medical and device management, as well as risk stratification. Women with a known diagnosis of a cardiomyopathy will often require continuation of drug therapy, which has the potential to exert negative effects on the foetus. This position paper assists in balancing benefits and detrimental effects.[GRAPHICS]",
keywords = "Heart failure, Pregnancy, Cancer, 2016 ESC GUIDELINES, IRON-DEFICIENCY, DILATED CARDIOMYOPATHY, INTERNATIONAL SOCIETY, PRACTICAL GUIDANCE, CARDIAC OUTCOMES, CHILDHOOD-CANCER, WORKING GROUP, TRANSPLANT, REGISTRY",
author = "Karen Sliwa and {van der Meer}, Peter and Petrie, {Mark C.} and Alexandra Frogoudaki and Johnson, {Mark R.} and Denise Hilfiker-Kleiner and Righab Hamdan and Jackson, {Alice M.} and Bassem Ibrahim and Amam Mbakwem and Carsten Tschoepe and Vera Regitz-Zagrosek and Elmir Omerovic and Jolien Roos-Hesselink and Michael Gatzoulis and Oktay Tutarel and Susanna Price and Stephane Heymans and Coats, {Andrew J. S.} and Christian Mueller and Ovidiu Chioncel and Thomas Thum and {de Boer}, {Rudolf A.} and Ewa Jankowska and Piotr Ponikowski and Lyon, {Alexander R.} and Giuseppe Rosano and Seferovic, {Petar M.} and Johann Bauersachs",
note = "Funding Information: J Bauersachs was supported by the Deutsche Forschungsgemeinschaft, Clinical Research Group 311 (KFO 311) {\textquoteleft}(Pre-)terminal heart and lung failure: unloading and repair{\textquoteright}. Conflict of interest: P.M. reports grants and personal fees from Vifor Pharma, personal fees from Novartis, grants from Ionis, personal fees from Servier, personal fees from Pharmacosmos, grants from Pfizer, grants from Astra Zeneca, outside the submitted work. S.H. reports personal fees from Astra Zeneca, personal fees from Cell Prothera, outside the submitted work. A.J.C. reports personal fees from Astra Zeneca, personal fees from Bayer, personal fees from Boehringer Ingelheim, personal fees from Menarini, personal fees from Novartis, personal fees from Nutricia, personal fees from Servier, personal fees from Vifor, personal fees from Abbott, personal fees from Actimed, personal fees from Arena, personal fees from Cardiac Dimensions, personal fees from Corvia, personal fees from CVRx, personal fees from Enopace, personal fees from ESN Cleer, personal fees from Faraday, personal fees from Gore, personal fees from Impulse Dynamics, personal fees from Respicardia, outside the submitted work. C.M. reports grants, personal fees and non-financial support from Several diagnostic companies, outside the submitted work Respicardia, outside the submitted work. Publisher Copyright: {\textcopyright} 2021 The Authors. European Journal of Heart Failure published by John Wiley & Sons Ltd on behalf of European Society of Cardiology.",
year = "2021",
month = apr,
doi = "10.1002/ejhf.2133",
language = "English",
volume = "23",
pages = "527--540",
journal = "European journal of heart failure",
issn = "1388-9842",
publisher = "John Wiley & Sons Inc.",
number = "4",
}