TY - JOUR
T1 - Risk stratification and management of women with cardiomyopathy/heart failure planning pregnancy or presenting during/after pregnancy
T2 - a position statement from the Heart Failure Association of the European Society of Cardiology Study Group on Peripartum Cardiomyopathy
AU - Sliwa, Karen
AU - van der Meer, Peter
AU - Petrie, Mark C.
AU - Frogoudaki, Alexandra
AU - Johnson, Mark R.
AU - Hilfiker-Kleiner, Denise
AU - Hamdan, Righab
AU - Jackson, Alice M.
AU - Ibrahim, Bassem
AU - Mbakwem, Amam
AU - Tschoepe, Carsten
AU - Regitz-Zagrosek, Vera
AU - Omerovic, Elmir
AU - Roos-Hesselink, Jolien
AU - Gatzoulis, Michael
AU - Tutarel, Oktay
AU - Price, Susanna
AU - Heymans, Stephane
AU - Coats, Andrew J. S.
AU - Mueller, Christian
AU - Chioncel, Ovidiu
AU - Thum, Thomas
AU - de Boer, Rudolf A.
AU - Jankowska, Ewa
AU - Ponikowski, Piotr
AU - Lyon, Alexander R.
AU - Rosano, Giuseppe
AU - Seferovic, Petar M.
AU - Bauersachs, Johann
N1 - Funding Information:
J Bauersachs was supported by the Deutsche Forschungsgemeinschaft, Clinical Research Group 311 (KFO 311) ‘(Pre-)terminal heart and lung failure: unloading and repair’. Conflict of interest: P.M. reports grants and personal fees from Vifor Pharma, personal fees from Novartis, grants from Ionis, personal fees from Servier, personal fees from Pharmacosmos, grants from Pfizer, grants from Astra Zeneca, outside the submitted work. S.H. reports personal fees from Astra Zeneca, personal fees from Cell Prothera, outside the submitted work. A.J.C. reports personal fees from Astra Zeneca, personal fees from Bayer, personal fees from Boehringer Ingelheim, personal fees from Menarini, personal fees from Novartis, personal fees from Nutricia, personal fees from Servier, personal fees from Vifor, personal fees from Abbott, personal fees from Actimed, personal fees from Arena, personal fees from Cardiac Dimensions, personal fees from Corvia, personal fees from CVRx, personal fees from Enopace, personal fees from ESN Cleer, personal fees from Faraday, personal fees from Gore, personal fees from Impulse Dynamics, personal fees from Respicardia, outside the submitted work. C.M. reports grants, personal fees and non-financial support from Several diagnostic companies, outside the submitted work Respicardia, outside the submitted work.
Publisher Copyright:
© 2021 The Authors. European Journal of Heart Failure published by John Wiley & Sons Ltd on behalf of European Society of Cardiology.
PY - 2021/4
Y1 - 2021/4
N2 - This position paper focusses on the pathophysiology, diagnosis and management of women diagnosed with a cardiomyopathy, or at risk of heart failure (HF), who are planning to conceive or present with (de novo or previously unknown) HF during or after pregnancy. This includes the heterogeneous group of heart muscle diseases such as hypertrophic, dilated, arrhythmogenic right ventricular and non-classified cardiomyopathies, left ventricular non-compaction, peripartum cardiomyopathy, Takotsubo syndrome, adult congenital heart disease with HF, and patients with right HF. Also, patients with a history of chemo-/radiotherapy for cancer or haematological malignancies need specific pre-, during and post-pregnancy assessment and counselling. We summarize the current knowledge about pathophysiological mechanisms, including gene mutations, clinical presentation, diagnosis, and medical and device management, as well as risk stratification. Women with a known diagnosis of a cardiomyopathy will often require continuation of drug therapy, which has the potential to exert negative effects on the foetus. This position paper assists in balancing benefits and detrimental effects.[GRAPHICS]
AB - This position paper focusses on the pathophysiology, diagnosis and management of women diagnosed with a cardiomyopathy, or at risk of heart failure (HF), who are planning to conceive or present with (de novo or previously unknown) HF during or after pregnancy. This includes the heterogeneous group of heart muscle diseases such as hypertrophic, dilated, arrhythmogenic right ventricular and non-classified cardiomyopathies, left ventricular non-compaction, peripartum cardiomyopathy, Takotsubo syndrome, adult congenital heart disease with HF, and patients with right HF. Also, patients with a history of chemo-/radiotherapy for cancer or haematological malignancies need specific pre-, during and post-pregnancy assessment and counselling. We summarize the current knowledge about pathophysiological mechanisms, including gene mutations, clinical presentation, diagnosis, and medical and device management, as well as risk stratification. Women with a known diagnosis of a cardiomyopathy will often require continuation of drug therapy, which has the potential to exert negative effects on the foetus. This position paper assists in balancing benefits and detrimental effects.[GRAPHICS]
KW - Heart failure
KW - Pregnancy
KW - Cancer
KW - 2016 ESC GUIDELINES
KW - IRON-DEFICIENCY
KW - DILATED CARDIOMYOPATHY
KW - INTERNATIONAL SOCIETY
KW - PRACTICAL GUIDANCE
KW - CARDIAC OUTCOMES
KW - CHILDHOOD-CANCER
KW - WORKING GROUP
KW - TRANSPLANT
KW - REGISTRY
U2 - 10.1002/ejhf.2133
DO - 10.1002/ejhf.2133
M3 - Article
C2 - 33609068
SN - 1388-9842
VL - 23
SP - 527
EP - 540
JO - European journal of heart failure
JF - European journal of heart failure
IS - 4
ER -