Risk Factors for Late-Onset Sepsis in Preterm Infants: A Multicenter Case-Control Study

Sofia el Manouni el Hassani; Daniel J. C. Berkhout; Hendrik J. Niemarkt; Sarah Mann; Willem P. de Boode; Veerle Cossey; Christian V. Hulzebos; Anton H. van Kaam; Boris W. Kramer; Richard A. van Lingen; Johannes B. van Goudoever; Daniel C. Vijlbrief; Mirjam M. van Weissenbruch; Marc A. Benninga; Nanne K. H. de Boer; Tim G. J. de Meij

doi:10.1159/000497781

Risk Factors for Late-Onset Sepsis in Preterm Infants: A Multicenter Case-Control Study

Sofia el Manouni el Hassani^*, Daniel J. C. Berkhout, Hendrik J. Niemarkt, Sarah Mann, Willem P. de Boode, Veerle Cossey, Christian V. Hulzebos, Anton H. van Kaam, Boris W. Kramer, Richard A. van Lingen, Johannes B. van Goudoever, Daniel C. Vijlbrief, Mirjam M. van Weissenbruch, Marc A. Benninga, Nanne K. H. de Boer, Tim G. J. de Meij

^*Corresponding author for this work

Research output: Contribution to journal › Article › Academic › peer-review

Abstract

Background: Late-onset sepsis (LOS) in preterm infants is a leading cause of mortality and morbidity. Timely recognition and initiation of antibiotics are important factors for improved outcomes. Identification of risk factors could allow selection of infants at an increased risk for LOS. Objectives: The aim was to identify risk factors for LOS. Methods: In this multicenter case-control study, preterm infants born at

Original language	English
Pages (from-to)	42-51
Number of pages	10
Journal	Neonatology
Volume	116
Issue number	1
DOIs	https://doi.org/10.1159/000497781
Publication status	Published - 2019

Keywords

Risk factors
Parenteral feeding
Breast feeding
Late-onset sepsis
Coagulase-negative staphylococcus
BLOOD-STREAM INFECTION
WEIGHT INFANTS
DWELL TIME
HUMAN-MILK
OUTCOMES

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Cite this

el Hassani, S. E. M., Berkhout, D. J. C., Niemarkt, H. J., Mann, S., de Boode, W. P., Cossey, V., Hulzebos, C. V., van Kaam, A. H., Kramer, B. W., van Lingen, R. A., van Goudoever, J. B., Vijlbrief, D. C., van Weissenbruch, M. M., Benninga, M. A., de Boer, N. K. H., & de Meij, T. G. J. (2019). Risk Factors for Late-Onset Sepsis in Preterm Infants: A Multicenter Case-Control Study. Neonatology, 116(1), 42-51. https://doi.org/10.1159/000497781

@article{93aaf46b361345bc9093ebe0c42beceb,

title = "Risk Factors for Late-Onset Sepsis in Preterm Infants: A Multicenter Case-Control Study",

abstract = "Background: Late-onset sepsis (LOS) in preterm infants is a leading cause of mortality and morbidity. Timely recognition and initiation of antibiotics are important factors for improved outcomes. Identification of risk factors could allow selection of infants at an increased risk for LOS. Objectives: The aim was to identify risk factors for LOS. Methods: In this multicenter case-control study, preterm infants born at",

keywords = "Risk factors, Parenteral feeding, Breast feeding, Late-onset sepsis, Coagulase-negative staphylococcus, BLOOD-STREAM INFECTION, WEIGHT INFANTS, DWELL TIME, HUMAN-MILK, OUTCOMES",

author = "{el Hassani}, {Sofia el Manouni} and Berkhout, {Daniel J. C.} and Niemarkt, {Hendrik J.} and Sarah Mann and {de Boode}, {Willem P.} and Veerle Cossey and Hulzebos, {Christian V.} and {van Kaam}, {Anton H.} and Kramer, {Boris W.} and {van Lingen}, {Richard A.} and {van Goudoever}, {Johannes B.} and Vijlbrief, {Daniel C.} and {van Weissenbruch}, {Mirjam M.} and Benninga, {Marc A.} and {de Boer}, {Nanne K. H.} and {de Meij}, {Tim G. J.}",

note = "Publisher Copyright: {\textcopyright} 2019.",

year = "2019",

doi = "10.1159/000497781",

language = "English",

volume = "116",

pages = "42--51",

journal = "Neonatology",

issn = "1661-7800",

publisher = "Karger",

number = "1",

}

el Hassani, SEM, Berkhout, DJC, Niemarkt, HJ, Mann, S, de Boode, WP, Cossey, V, Hulzebos, CV, van Kaam, AH, Kramer, BW, van Lingen, RA, van Goudoever, JB, Vijlbrief, DC, van Weissenbruch, MM, Benninga, MA, de Boer, NKH & de Meij, TGJ 2019, 'Risk Factors for Late-Onset Sepsis in Preterm Infants: A Multicenter Case-Control Study', Neonatology, vol. 116, no. 1, pp. 42-51. https://doi.org/10.1159/000497781

TY - JOUR

T1 - Risk Factors for Late-Onset Sepsis in Preterm Infants

T2 - A Multicenter Case-Control Study

AU - el Hassani, Sofia el Manouni

AU - Berkhout, Daniel J. C.

AU - Niemarkt, Hendrik J.

AU - Mann, Sarah

AU - de Boode, Willem P.

AU - Cossey, Veerle

AU - Hulzebos, Christian V.

AU - van Kaam, Anton H.

AU - Kramer, Boris W.

AU - van Lingen, Richard A.

AU - van Goudoever, Johannes B.

AU - Vijlbrief, Daniel C.

AU - van Weissenbruch, Mirjam M.

AU - Benninga, Marc A.

AU - de Boer, Nanne K. H.

AU - de Meij, Tim G. J.

PY - 2019

Y1 - 2019

N2 - Background: Late-onset sepsis (LOS) in preterm infants is a leading cause of mortality and morbidity. Timely recognition and initiation of antibiotics are important factors for improved outcomes. Identification of risk factors could allow selection of infants at an increased risk for LOS. Objectives: The aim was to identify risk factors for LOS. Methods: In this multicenter case-control study, preterm infants born at

AB - Background: Late-onset sepsis (LOS) in preterm infants is a leading cause of mortality and morbidity. Timely recognition and initiation of antibiotics are important factors for improved outcomes. Identification of risk factors could allow selection of infants at an increased risk for LOS. Objectives: The aim was to identify risk factors for LOS. Methods: In this multicenter case-control study, preterm infants born at

KW - Risk factors

KW - Parenteral feeding

KW - Breast feeding

KW - Late-onset sepsis

KW - Coagulase-negative staphylococcus

KW - BLOOD-STREAM INFECTION

KW - WEIGHT INFANTS

KW - DWELL TIME

KW - HUMAN-MILK

KW - OUTCOMES

U2 - 10.1159/000497781

DO - 10.1159/000497781

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SN - 1661-7800

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JF - Neonatology

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