Risk factors for explantation of iris-fixated phakic intraocular lenses

Soraya M. R. Jonker*, Annelies A. C. Van Averbeke, Tos T. J. M. Berendschot, Isabelle E. Y. Saelens, Rudy M. M. A. Nuijts

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

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Abstract

Purpose: To determine risk factors for explantation of iris-fixated phakic intraocular lenses (pIOLs) with a maximum 17-year follow-up.

Setting: University Eye Clinic Maastricht, Maastricht UMC+, the Netherlands.

Design: Prospective case series.

Methods: Eyes that had implantation of 1 of various iris-fixated pIOL models from 1998 to 2016 were evaluated. Primary outcome measures were the rate and proportion of pIOL explantations and the survival time (ie, time to pIOL explantation) in general and specifically as a result of cataract formation or endothelial cell loss (ECL).

Results: The study comprised 1037 eyes. The mean follow-up was 69.3 months 52.8 (SD) and the mean preoperative age, 40.2 +/- 10.9 years. The overall explantation rate was 12% after a mean of 166.1 months +/- 3.0 (standard error). Phakic IOL explantations were performed in 59% of eyes because of cataract formation and in 32% because of ECL. Shorter survival was seen with a higher preoperative age (hazard ratio [HP], 1.07/y; P

Conclusions: The explantation rate of iris-fixated pIOLs was 12% after almost 14 years of follow-up, with 59% of pIOL explantations caused by cataract formation and 32% caused by ECL. An older preoperative age, longer AL, and smaller ACD were risk factors for a shorter survival. (C) 2019 ASCRS and ESCRS

Original languageEnglish
Pages (from-to)1092-1098
Number of pages7
JournalJournal of Cataract and Refractive Surgery
Volume45
Issue number8
DOIs
Publication statusPublished - Aug 2019
Event36th Congress of the European Society of Cataract and Refractive Surgeons - Reed Messe, Vienna, Austria
Duration: 22 Sept 201826 Sept 2018

Keywords

  • ENDOTHELIAL-CELL LOSS
  • 5-YEAR FOLLOW-UP
  • LONG-TERM
  • HIGH MYOPIA
  • SPECULAR MICROSCOPE
  • IMPLANTATION
  • CORNEAL
  • MODERATE
  • EYES
  • MULTICENTER

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