TY - JOUR
T1 - Risk factors for explantation of iris-fixated phakic intraocular lenses
AU - Jonker, Soraya M. R.
AU - Van Averbeke, Annelies A. C.
AU - Berendschot, Tos T. J. M.
AU - Saelens, Isabelle E. Y.
AU - Nuijts, Rudy M. M. A.
N1 - Funding Information:
Dr. Nuijts receives grants from Abbot Medical Optics, Inc. , Bausch & Lomb ,Inc., Carl Zeiss Meditec AG , HumanOptics AG , Oculentis , and Ophtec BV; grants and personal fees from Alcon Laboratories, Inc .; and personal fees from ASICO LLC and Théa Pharma GmbH, all outside the submitted work. None of the other authors has a financial or proprietary interest in any material or method mentioned.
Funding Information:
Dr. Nuijts receives grants from Abbot Medical Optics, Inc., Bausch & Lomb,Inc., Carl Zeiss Meditec AG, HumanOptics AG, Oculentis, and Ophtec BV; grants and personal fees from Alcon Laboratories, Inc.; and personal fees from ASICO LLC and Th?a Pharma GmbH, all outside the submitted work. None of the other authors has a financial or proprietary interest in any material or method mentioned.
Publisher Copyright:
© 2019 ASCRS and ESCRS
PY - 2019/8
Y1 - 2019/8
N2 - Purpose: To determine risk factors for explantation of iris-fixated phakic intraocular lenses (pIOLs) with a maximum 17-year follow-up.Setting: University Eye Clinic Maastricht, Maastricht UMC+, the Netherlands.Design: Prospective case series.Methods: Eyes that had implantation of 1 of various iris-fixated pIOL models from 1998 to 2016 were evaluated. Primary outcome measures were the rate and proportion of pIOL explantations and the survival time (ie, time to pIOL explantation) in general and specifically as a result of cataract formation or endothelial cell loss (ECL).Results: The study comprised 1037 eyes. The mean follow-up was 69.3 months 52.8 (SD) and the mean preoperative age, 40.2 +/- 10.9 years. The overall explantation rate was 12% after a mean of 166.1 months +/- 3.0 (standard error). Phakic IOL explantations were performed in 59% of eyes because of cataract formation and in 32% because of ECL. Shorter survival was seen with a higher preoperative age (hazard ratio [HP], 1.07/y; PConclusions: The explantation rate of iris-fixated pIOLs was 12% after almost 14 years of follow-up, with 59% of pIOL explantations caused by cataract formation and 32% caused by ECL. An older preoperative age, longer AL, and smaller ACD were risk factors for a shorter survival. (C) 2019 ASCRS and ESCRS
AB - Purpose: To determine risk factors for explantation of iris-fixated phakic intraocular lenses (pIOLs) with a maximum 17-year follow-up.Setting: University Eye Clinic Maastricht, Maastricht UMC+, the Netherlands.Design: Prospective case series.Methods: Eyes that had implantation of 1 of various iris-fixated pIOL models from 1998 to 2016 were evaluated. Primary outcome measures were the rate and proportion of pIOL explantations and the survival time (ie, time to pIOL explantation) in general and specifically as a result of cataract formation or endothelial cell loss (ECL).Results: The study comprised 1037 eyes. The mean follow-up was 69.3 months 52.8 (SD) and the mean preoperative age, 40.2 +/- 10.9 years. The overall explantation rate was 12% after a mean of 166.1 months +/- 3.0 (standard error). Phakic IOL explantations were performed in 59% of eyes because of cataract formation and in 32% because of ECL. Shorter survival was seen with a higher preoperative age (hazard ratio [HP], 1.07/y; PConclusions: The explantation rate of iris-fixated pIOLs was 12% after almost 14 years of follow-up, with 59% of pIOL explantations caused by cataract formation and 32% caused by ECL. An older preoperative age, longer AL, and smaller ACD were risk factors for a shorter survival. (C) 2019 ASCRS and ESCRS
KW - ENDOTHELIAL-CELL LOSS
KW - 5-YEAR FOLLOW-UP
KW - LONG-TERM
KW - HIGH MYOPIA
KW - SPECULAR MICROSCOPE
KW - IMPLANTATION
KW - CORNEAL
KW - MODERATE
KW - EYES
KW - MULTICENTER
U2 - 10.1016/j.jcrs.2019.03.009
DO - 10.1016/j.jcrs.2019.03.009
M3 - Article
C2 - 31371006
SN - 0886-3350
VL - 45
SP - 1092
EP - 1098
JO - Journal of Cataract and Refractive Surgery
JF - Journal of Cataract and Refractive Surgery
IS - 8
T2 - 36th Congress of the European Society of Cataract and Refractive Surgeons
Y2 - 22 September 2018 through 26 September 2018
ER -