TY - JOUR
T1 - Risk Factors for Atrial Fibrillation Progression
AU - Heijman, Jordi
AU - Luermans, Justin G L M
AU - Linz, Dominik
AU - van Gelder, Isabelle C
AU - Crijns, Harry J G M
N1 - Copyright © 2020 Elsevier Inc. All rights reserved.
PY - 2021/3
Y1 - 2021/3
N2 - Atrial fibrillation is a chronic, progressive condition that presents a major health burden. This review summarizes recent studies assessing atrial fibrillation progression and its associated risk factors, describes the mechanisms underlying atrial fibrillation progression, and discusses the clinical implications of the progressive nature of atrial fibrillation. Progression of atrial fibrillation burden, and clinical progression from paroxysmal to more advanced (persistent/permanent) forms is common, but progression rates are variable. Atrial fibrillation progression parallels progressive atrial remodeling induced by atrial fibrillation risk factors and atrial fibrillation itself, and is associated with worse clinical outcomes.
AB - Atrial fibrillation is a chronic, progressive condition that presents a major health burden. This review summarizes recent studies assessing atrial fibrillation progression and its associated risk factors, describes the mechanisms underlying atrial fibrillation progression, and discusses the clinical implications of the progressive nature of atrial fibrillation. Progression of atrial fibrillation burden, and clinical progression from paroxysmal to more advanced (persistent/permanent) forms is common, but progression rates are variable. Atrial fibrillation progression parallels progressive atrial remodeling induced by atrial fibrillation risk factors and atrial fibrillation itself, and is associated with worse clinical outcomes.
KW - Atrial Fibrillation/epidemiology
KW - Disease Progression
KW - Heart Disease Risk Factors
KW - Humans
U2 - 10.1016/j.ccep.2020.10.011
DO - 10.1016/j.ccep.2020.10.011
M3 - (Systematic) Review article
C2 - 33516398
SN - 1877-9182
VL - 13
SP - 201
EP - 209
JO - Cardiac Electrophysiology Clinics
JF - Cardiac Electrophysiology Clinics
IS - 1
ER -