Risk assessment after acute myocardial infarction: Role of novel biomarkers and implications for early discharge

Dirk Adrianus Alouijsius Maria Schellings

Research output: ThesisDoctoral ThesisExternal prepared

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Myocardial infarction is a serious condition caused by a sudden occlusion of a coronary artery. Myocardial infarction is associated with loss of myocardial tissue, decrease in pump function and potentially fatal arrhythmias. Percutaneous angioplasty of the occluded coronary artery markedly improves the prognosis by decreasing mortality rates and arrhythmias, and improving the remaining pump function. As a result, the length of hospital stay, which is currently approximately 4-7 days, can be reduced.
This dissertation shows how the mortality risk can be determined at an early stage by adding a biomarker (to be measured in blood) to an existing risk score. More than half of patients have a low mortality risk and can therefore be safely discharged from hospital within 48 hours of admission.
Original languageEnglish
Awarding Institution
  • Maastricht University
  • Hoorntje, Jan, Supervisor
  • van 't Hof, Arnoud, Co-Supervisor
  • Adiyaman, A., Co-Supervisor, External person
Award date12 Apr 2017
Place of PublicationMaastricht
Print ISBNs978-94-6233-547-9
Publication statusPublished - 2017


  • myocardial infarction
  • mortality risk score
  • biomarker

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