Rifampicin, not vitamin E, suppresses parenteral nutrition-associated liver disease development through the pregnane X receptor pathway in piglets

Gregory Guthrie*, Barbara Stoll, Shaji Chacko, Charlotte Lauridsen, Jogchum Plat, Douglas Burrin

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

Original languageEnglish
Pages (from-to)G41-G52
Number of pages12
JournalAmerican Journal of Physiology-Gastrointestinal and Liver Physiology
Volume318
Issue number1
DOIs
Publication statusPublished - Jan 2020

Keywords

  • bile acid metabolism
  • cholestasis
  • parenteral nutrition-associated liver disease
  • rifampicin
  • alpha-tocopherol
  • vitamin E
  • FAT OVERLOAD SYNDROME
  • ALPHA-TOCOPHEROL
  • LIPID EMULSION
  • FISH-OIL
  • ABC TRANSPORTERS
  • ACID
  • BILE
  • METABOLISM
  • EXPRESSION
  • INFANTS

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