Review of the Series "Disease of the Year 2011: Toxoplasmosis" Pathophysiology of Toxoplasmosis

Carlos S. Subauste*, Daniel Ajzenberg, Aize Kijlstra

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

22 Citations (Web of Science)

Abstract

Toxoplasma gondii is a major cause of chronic parasitic infection in the world. This protozoan can cause retino-choroiditis in newborns and in adults, both immunocompetent and immunodeficient. This disease tends to be recurrent and can lead to severe visual impairment. The authors review current knowledge on the role of parasite genetics in influencing susceptibility to ocular toxoplasmosis and on the immuno-pathogenesis of this disease.
Original languageEnglish
Pages (from-to)297-306
JournalOcular Immunology and Inflammation
Volume19
Issue number5
DOIs
Publication statusPublished - Oct 2011

Keywords

  • genetics
  • immunology
  • parasite
  • retinitis
  • uveitis

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