Resveratrol: A booster of mitochondria

Marlies de Ligt

Research output: ThesisDoctoral ThesisInternal

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Resveratrol is a naturally occurring substance found in red wine. Animal studies have found positive health effects of resveratrol. This dissertation researched whether similar effects could also be found in human subjects and whether the substance could be used to prevent and treat type 2 diabetes. We can conclude that resveratrol significantly boosts mitochondrial function (the so-called energy factories in our muscles). However, it is unclear whether these improvements in mitochondrial function are enough to improve insulin sensitivity and therefore to determine whether resveratrol can be used to treat diabetes.
Original languageEnglish
Awarding Institution
  • Maastricht University
  • Schrauwen, Patrick, Supervisor
  • Schrauwen - Hinderling, Vera, Co-Supervisor
  • Phielix, Esther, Co-Supervisor
Award date26 Oct 2018
Place of PublicationMaastricht
Print ISBNs9789493014527
Publication statusPublished - 2018


  • type 2 diabetes
  • nutritional supplement
  • mitochondrial function
  • insulin sensitivity
  • human research studies

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