Response to Vaccination in Infants Exposed to Antitumor Necrosis Factor Alpha In Utero

J.W. Wieringa*, R.H.T. van Beek, L.W. Rovekamp, G.J.A. Driessen, H.M. van Wering

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

Abstract

In this retrospective cohort study, the response to routinely administered Haemophilus influenzae type B vaccine, pneumococcal and pertussis vaccinations in 27 children exposed to antitumor necrosis factor alpha (anti-TNF alpha) during pregnancy was measured. The overall vaccination response seems comparable for children exposed to anti-TNF alpha and healthy infants. After primary vaccination series, inadequate response was present in some patients and might be related to exposure to anti-TNF alpha.
Original languageEnglish
Pages (from-to)912-916
Number of pages5
JournalPediatric Infectious Disease Journal
Volume40
Issue number10
DOIs
Publication statusPublished - 1 Oct 2021

Keywords

  • infant
  • vaccination
  • anti-TNF alpha
  • pregnancy
  • immune system
  • INFLAMMATORY-BOWEL-DISEASE
  • PERTUSSIS
  • THERAPY

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