Respiratory and metabolic health: the impact of body composition

Alina Ofenheimer

Research output: ThesisDoctoral ThesisExternal prepared

121 Downloads (Pure)

Abstract

This thesis provides the first reference values and charts for different body compartments assessed by Dual Energy X-ray absorptiometry (DXA) based on a Caucasian European cohort aged 6 to 81 years. For individuals with DXA measurements, it provides a tool which enables them to compare their results to the general population. It further shows that we need to consider fat and muscle mass when investigating and evaluating metabolic and respiratory health. The data show that children with high fat and muscle mass have the most adverse blood lipid profile. It will be important to observe their future cardiometabolic outcomes to estimate their risk for cardiovascular diseases. The current thesis further found that individuals with higher muscle mass have a better lung function and that gain in muscle mass is associated with a higher lung function increase in childhood. On the contrary, individuals with higher fat mass had lower lung function, and this effect was stronger in adulthood.
Original languageEnglish
QualificationDoctor of Philosophy
Awarding Institution
  • Maastricht University
Supervisors/Advisors
  • Wouters, Emiel, Supervisor
  • Franssen, Frits, Supervisor
  • Breyer, M.K., Co-Supervisor, External person
  • Breyer-Kohansal, R., Co-Supervisor, External person
Award date10 Jun 2024
Place of PublicationMaastricht
Publisher
Print ISBNs9789464699890
DOIs
Publication statusPublished - 2024

Keywords

  • Body composition
  • lung health
  • metabolic health
  • muscle and fat mass

Fingerprint

Dive into the research topics of 'Respiratory and metabolic health: the impact of body composition'. Together they form a unique fingerprint.

Cite this