Residual Glandular Breast Tissue After Mastectomy: A Systematic Review

Orit Kaidar-Person; Liesbeth J. Boersma; Philip Poortmans; Miri Sklair-Levy; Birgitte Vrou Offersen; Maria-Joao Cardoso; Dirk de Ruysscher

doi:10.1245/s10434-020-08516-4

Residual Glandular Breast Tissue After Mastectomy: A Systematic Review

Orit Kaidar-Person^*, Liesbeth J. Boersma, Philip Poortmans, Miri Sklair-Levy, Birgitte Vrou Offersen, Maria-Joao Cardoso, Dirk de Ruysscher

^*Corresponding author for this work

Research output: Contribution to journal › (Systematic) Review article › peer-review

Abstract

Background The goal of mastectomy is remove all of the glandular breast tissue (BGT) without compromising skin flaps viability. The purpose of this systematic review was to localize and/or estimate the amount of residual BGT (rBGT) after mastectomy and to identify factors that could be related to rBGT and/or residual disease. Methods We conducted a PubMed search. The report was subdivided according to the method used to evaluate the presence of rBGT. A total of 16 publications were included in our final report. Two main methods for identifying rBGT included imaging (i.e., MRI scan) and histological evaluation at the time of mastectomy. Results The rate of rBGT was reported in up to 100% of the patients and was found to be associated mainly with the type of surgical resection, indication, and surgeon's expertise. Residual breast tissue can be found in all areas of the remaining chest wall, mostly in the skin-flaps, and more frequently underneath the nipple-areola complex.

Original language	English
Pages (from-to)	2288-2296
Number of pages	9
Journal	Annals of Surgical Oncology
Volume	27
Issue number	7
DOIs	https://doi.org/10.1245/s10434-020-08516-4
Publication status	Published - Jul 2020

Keywords

DUCT LOBULAR UNITS
POSTMASTECTOMY RADIATION-THERAPY
SKIN-SPARING MASTECTOMY
IMMEDIATE RECONSTRUCTION
MUTATION CARRIERS
NIPPLE
CANCER
INVOLVEMENT
CARCINOMA
TRENDS

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@article{52a0c6e111844d2081d66a0591b460e6,

title = "Residual Glandular Breast Tissue After Mastectomy: A Systematic Review",

abstract = "Background The goal of mastectomy is remove all of the glandular breast tissue (BGT) without compromising skin flaps viability. The purpose of this systematic review was to localize and/or estimate the amount of residual BGT (rBGT) after mastectomy and to identify factors that could be related to rBGT and/or residual disease. Methods We conducted a PubMed search. The report was subdivided according to the method used to evaluate the presence of rBGT. A total of 16 publications were included in our final report. Two main methods for identifying rBGT included imaging (i.e., MRI scan) and histological evaluation at the time of mastectomy. Results The rate of rBGT was reported in up to 100\% of the patients and was found to be associated mainly with the type of surgical resection, indication, and surgeon's expertise. Residual breast tissue can be found in all areas of the remaining chest wall, mostly in the skin-flaps, and more frequently underneath the nipple-areola complex.",

keywords = "DUCT LOBULAR UNITS, POSTMASTECTOMY RADIATION-THERAPY, SKIN-SPARING MASTECTOMY, IMMEDIATE RECONSTRUCTION, MUTATION CARRIERS, NIPPLE, CANCER, INVOLVEMENT, CARCINOMA, TRENDS",

author = "Orit Kaidar-Person and Boersma, \{Liesbeth J.\} and Philip Poortmans and Miri Sklair-Levy and Offersen, \{Birgitte Vrou\} and Maria-Joao Cardoso and \{de Ruysscher\}, Dirk",

note = "Publisher Copyright: {\textcopyright} 2020, Society of Surgical Oncology.",

year = "2020",

month = jul,

doi = "10.1245/s10434-020-08516-4",

language = "English",

volume = "27",

pages = "2288--2296",

journal = "Annals of Surgical Oncology",

issn = "1068-9265",

publisher = "Springer",

number = "7",

}

TY - JOUR

T1 - Residual Glandular Breast Tissue After Mastectomy

T2 - A Systematic Review

AU - Kaidar-Person, Orit

AU - Boersma, Liesbeth J.

AU - Poortmans, Philip

AU - Sklair-Levy, Miri

AU - Offersen, Birgitte Vrou

AU - Cardoso, Maria-Joao

AU - de Ruysscher, Dirk

PY - 2020/7

Y1 - 2020/7

N2 - Background The goal of mastectomy is remove all of the glandular breast tissue (BGT) without compromising skin flaps viability. The purpose of this systematic review was to localize and/or estimate the amount of residual BGT (rBGT) after mastectomy and to identify factors that could be related to rBGT and/or residual disease. Methods We conducted a PubMed search. The report was subdivided according to the method used to evaluate the presence of rBGT. A total of 16 publications were included in our final report. Two main methods for identifying rBGT included imaging (i.e., MRI scan) and histological evaluation at the time of mastectomy. Results The rate of rBGT was reported in up to 100% of the patients and was found to be associated mainly with the type of surgical resection, indication, and surgeon's expertise. Residual breast tissue can be found in all areas of the remaining chest wall, mostly in the skin-flaps, and more frequently underneath the nipple-areola complex.

AB - Background The goal of mastectomy is remove all of the glandular breast tissue (BGT) without compromising skin flaps viability. The purpose of this systematic review was to localize and/or estimate the amount of residual BGT (rBGT) after mastectomy and to identify factors that could be related to rBGT and/or residual disease. Methods We conducted a PubMed search. The report was subdivided according to the method used to evaluate the presence of rBGT. A total of 16 publications were included in our final report. Two main methods for identifying rBGT included imaging (i.e., MRI scan) and histological evaluation at the time of mastectomy. Results The rate of rBGT was reported in up to 100% of the patients and was found to be associated mainly with the type of surgical resection, indication, and surgeon's expertise. Residual breast tissue can be found in all areas of the remaining chest wall, mostly in the skin-flaps, and more frequently underneath the nipple-areola complex.

KW - DUCT LOBULAR UNITS

KW - POSTMASTECTOMY RADIATION-THERAPY

KW - SKIN-SPARING MASTECTOMY

KW - IMMEDIATE RECONSTRUCTION

KW - MUTATION CARRIERS

KW - NIPPLE

KW - CANCER

KW - INVOLVEMENT

KW - CARCINOMA

KW - TRENDS

U2 - 10.1245/s10434-020-08516-4

DO - 10.1245/s10434-020-08516-4

M3 - (Systematic) Review article

C2 - 32390098

SN - 1068-9265

VL - 27

SP - 2288

EP - 2296

JO - Annals of Surgical Oncology

JF - Annals of Surgical Oncology

IS - 7

ER -

Residual Glandular Breast Tissue After Mastectomy: A Systematic Review

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Keywords

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