Report from a multidisciplinary meeting on anxiety as a non-motor manifestation of Parkinson's disease

Gregory M. Pontone*, Nadeeka Dissanayka, Liana Apostolova, Richard G. Brown, Roseanne Dobkin, Kathy Dujardin, Joseph H. Friedman, Albert F. G. Leentjens, Eric J. Lenze, Laura Marsh, Lynda Mari, Oury Monchi, Irene H. Richard, Anette Schrag, Antonio P. Strafella, Beth Vernaleo, Daniel Weintraub, Zoltan Mari

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review

20 Citations (Web of Science)

Abstract

Anxiety is a severe problem for at least one-third of people living with Parkinson's disease (PD). Anxiety appears to have a greater adverse impact on quality of life than motor impairment. Despite its high prevalence and impact on daily life, anxiety is often undiagnosed and untreated. To better address anxiety in PD, future research must improve knowledge about the mechanism of anxiety in PD and address the lack of empirical evidence from clinical trials. In response to these challenges, the Parkinson's Foundation sponsored an expert meeting on anxiety on June 13th and 14th 2018. This paper summarizes the findings from that meeting informed by a review of the existing literature and discussions among patients, caregivers, and an international, clinician-scientist, expert panel working group. The goal is to provide recommendations to improve our understanding and treatment of anxiety in PD.

Original languageEnglish
Article number30
Number of pages9
Journalnpj Parkinson's Disease
Volume5
DOIs
Publication statusPublished - 11 Dec 2019

Keywords

  • COGNITIVE-BEHAVIORAL THERAPY
  • QUALITY-OF-LIFE
  • NEUROPSYCHIATRIC SYMPTOMS
  • CONTROLLED-TRIAL
  • RATING-SCALES
  • PSYCHOSOCIAL INTERVENTIONS
  • STRESS REDUCTION
  • DOUBLE-BLIND
  • DEPRESSION
  • DISORDERS

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