Repolarization instability and arrhythmia by I-Kr block in single human-induced pluripotent stem cell-derived cardiomyocytes and 2D monolayers

Cristina Altrocchi, Tessa de Korte, Joyce Bernardi, Roel L. H. M. G. Spatjens, Stefan R. Braam, Jordi Heijman, Antonio Zaza, Paul G. A. Volders*

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

Original languageEnglish
Pages (from-to)1431-1441
Number of pages11
JournalEP Europace
Volume22
Issue number9
DOIs
Publication statusPublished - Sep 2020

Keywords

  • Human-induced pluripotent stem cell-derived cardiomyocytes
  • Ion channel
  • Calcium handling
  • Beat-to-beat variability of repolarization
  • Arrhythmia inducibility
  • Multi-electrode arrays
  • SODIUM CURRENT
  • CALCIUM
  • CURRENTS

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