Repetitive electrostatic pressurised intraperitoneal aerosol chemotherapy (ePIPAC) with oxaliplatin as a palliative monotherapy for isolated unresectable colorectal peritoneal metastases: protocol of a Dutch, multicentre, open-label, single-arm, phase II study (CRC-PIPAC)

Koen P. Rovers; Robin J. Lurvink; Emma C. E. Wassenaar; Thomas J. M. Kootstra; Harm J. Scholten; Rudaba Tajzai; Maarten J. Deenen; Joost Nederend; Max J. Lahaye; Clement J. R. Huysentruyt; Iris van't Erve; Remond J. A. Fijneman; Alexander Constantinides; Onno Kranenburg; Maartje Los; Anna M. J. Thijs; Geert-Jan M. Creemers; Jacobus W. A. Burger; Marinus J. Wiezer; Djamila Boerma; Simon W. Nienhuijs; Ignace H. J. T. de Hingh

doi:10.1136/bmjopen-2019-030408

Repetitive electrostatic pressurised intraperitoneal aerosol chemotherapy (ePIPAC) with oxaliplatin as a palliative monotherapy for isolated unresectable colorectal peritoneal metastases: protocol of a Dutch, multicentre, open-label, single-arm, phase II study (CRC-PIPAC)

Koen P. Rovers, Robin J. Lurvink, Emma C. E. Wassenaar, Thomas J. M. Kootstra, Harm J. Scholten, Rudaba Tajzai, Maarten J. Deenen, Joost Nederend, Max J. Lahaye, Clement J. R. Huysentruyt, Iris van't Erve, Remond J. A. Fijneman, Alexander Constantinides, Onno Kranenburg, Maartje Los, Anna M. J. Thijs, Geert-Jan M. Creemers, Jacobus W. A. Burger, Marinus J. Wiezer, Djamila BoermaSimon W. Nienhuijs, Ignace H. J. T. de Hingh^*

^*Corresponding author for this work

Research output: Contribution to journal › Article › Academic › peer-review

Original language	English
Article number	030408
Pages (from-to)	1-10
Number of pages	10
Journal	BMJ Open
Volume	9
Issue number	7
DOIs	https://doi.org/10.1136/bmjopen-2019-030408
Publication status	Published - Aug 2019

Keywords

QUALITY-OF-LIFE
INTRAABDOMINAL PRESSURE
1ST EVIDENCE
CANCER
PHARMACOKINETICS
CARCINOMATOSIS
SAFETY
CLASSIFICATION
QUESTIONNAIRE
PENETRATION

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10.1136/bmjopen-2019-030408

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Rovers, K. P., Lurvink, R. J., Wassenaar, E. C. E., Kootstra, T. J. M., Scholten, H. J., Tajzai, R., Deenen, M. J., Nederend, J., Lahaye, M. J., Huysentruyt, C. J. R., van't Erve, I., Fijneman, R. J. A., Constantinides, A., Kranenburg, O., Los, M., Thijs, A. M. J., Creemers, G-J. M., Burger, J. W. A., Wiezer, M. J., ... de Hingh, I. H. J. T. (2019). Repetitive electrostatic pressurised intraperitoneal aerosol chemotherapy (ePIPAC) with oxaliplatin as a palliative monotherapy for isolated unresectable colorectal peritoneal metastases: protocol of a Dutch, multicentre, open-label, single-arm, phase II study (CRC-PIPAC). BMJ Open, 9(7), 1-10. [030408]. https://doi.org/10.1136/bmjopen-2019-030408

Rovers, Koen P. ; Lurvink, Robin J. ; Wassenaar, Emma C. E. ; Kootstra, Thomas J. M. ; Scholten, Harm J. ; Tajzai, Rudaba ; Deenen, Maarten J. ; Nederend, Joost ; Lahaye, Max J. ; Huysentruyt, Clement J. R. ; van't Erve, Iris ; Fijneman, Remond J. A. ; Constantinides, Alexander ; Kranenburg, Onno ; Los, Maartje ; Thijs, Anna M. J. ; Creemers, Geert-Jan M. ; Burger, Jacobus W. A. ; Wiezer, Marinus J. ; Boerma, Djamila ; Nienhuijs, Simon W. ; de Hingh, Ignace H. J. T. / Repetitive electrostatic pressurised intraperitoneal aerosol chemotherapy (ePIPAC) with oxaliplatin as a palliative monotherapy for isolated unresectable colorectal peritoneal metastases : protocol of a Dutch, multicentre, open-label, single-arm, phase II study (CRC-PIPAC). In: BMJ Open. 2019 ; Vol. 9, No. 7. pp. 1-10.

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title = "Repetitive electrostatic pressurised intraperitoneal aerosol chemotherapy (ePIPAC) with oxaliplatin as a palliative monotherapy for isolated unresectable colorectal peritoneal metastases: protocol of a Dutch, multicentre, open-label, single-arm, phase II study (CRC-PIPAC)",

keywords = "QUALITY-OF-LIFE, INTRAABDOMINAL PRESSURE, 1ST EVIDENCE, CANCER, PHARMACOKINETICS, CARCINOMATOSIS, SAFETY, CLASSIFICATION, QUESTIONNAIRE, PENETRATION",

author = "Rovers, {Koen P.} and Lurvink, {Robin J.} and Wassenaar, {Emma C. E.} and Kootstra, {Thomas J. M.} and Scholten, {Harm J.} and Rudaba Tajzai and Deenen, {Maarten J.} and Joost Nederend and Lahaye, {Max J.} and Huysentruyt, {Clement J. R.} and {van't Erve}, Iris and Fijneman, {Remond J. A.} and Alexander Constantinides and Onno Kranenburg and Maartje Los and Thijs, {Anna M. J.} and Creemers, {Geert-Jan M.} and Burger, {Jacobus W. A.} and Wiezer, {Marinus J.} and Djamila Boerma and Nienhuijs, {Simon W.} and {de Hingh}, {Ignace H. J. T.}",

year = "2019",

month = aug,

doi = "10.1136/bmjopen-2019-030408",

language = "English",

volume = "9",

pages = "1--10",

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Rovers, KP, Lurvink, RJ, Wassenaar, ECE, Kootstra, TJM, Scholten, HJ, Tajzai, R, Deenen, MJ, Nederend, J, Lahaye, MJ, Huysentruyt, CJR, van't Erve, I, Fijneman, RJA, Constantinides, A, Kranenburg, O, Los, M, Thijs, AMJ, Creemers, G-JM, Burger, JWA, Wiezer, MJ, Boerma, D, Nienhuijs, SW & de Hingh, IHJT 2019, 'Repetitive electrostatic pressurised intraperitoneal aerosol chemotherapy (ePIPAC) with oxaliplatin as a palliative monotherapy for isolated unresectable colorectal peritoneal metastases: protocol of a Dutch, multicentre, open-label, single-arm, phase II study (CRC-PIPAC)', BMJ Open, vol. 9, no. 7, 030408, pp. 1-10. https://doi.org/10.1136/bmjopen-2019-030408

Repetitive electrostatic pressurised intraperitoneal aerosol chemotherapy (ePIPAC) with oxaliplatin as a palliative monotherapy for isolated unresectable colorectal peritoneal metastases : protocol of a Dutch, multicentre, open-label, single-arm, phase II study (CRC-PIPAC). / Rovers, Koen P.; Lurvink, Robin J.; Wassenaar, Emma C. E.; Kootstra, Thomas J. M.; Scholten, Harm J.; Tajzai, Rudaba; Deenen, Maarten J.; Nederend, Joost; Lahaye, Max J.; Huysentruyt, Clement J. R.; van't Erve, Iris; Fijneman, Remond J. A.; Constantinides, Alexander; Kranenburg, Onno; Los, Maartje; Thijs, Anna M. J.; Creemers, Geert-Jan M.; Burger, Jacobus W. A.; Wiezer, Marinus J.; Boerma, Djamila; Nienhuijs, Simon W.; de Hingh, Ignace H. J. T.

In: BMJ Open, Vol. 9, No. 7, 030408, 08.2019, p. 1-10.

Research output: Contribution to journal › Article › Academic › peer-review

TY - JOUR

T1 - Repetitive electrostatic pressurised intraperitoneal aerosol chemotherapy (ePIPAC) with oxaliplatin as a palliative monotherapy for isolated unresectable colorectal peritoneal metastases

T2 - protocol of a Dutch, multicentre, open-label, single-arm, phase II study (CRC-PIPAC)

AU - Rovers, Koen P.

AU - Lurvink, Robin J.

AU - Wassenaar, Emma C. E.

AU - Kootstra, Thomas J. M.

AU - Scholten, Harm J.

AU - Tajzai, Rudaba

AU - Deenen, Maarten J.

AU - Nederend, Joost

AU - Lahaye, Max J.

AU - Huysentruyt, Clement J. R.

AU - van't Erve, Iris

AU - Fijneman, Remond J. A.

AU - Constantinides, Alexander

AU - Kranenburg, Onno

AU - Los, Maartje

AU - Thijs, Anna M. J.

AU - Creemers, Geert-Jan M.

AU - Burger, Jacobus W. A.

AU - Wiezer, Marinus J.

AU - Boerma, Djamila

AU - Nienhuijs, Simon W.

AU - de Hingh, Ignace H. J. T.

PY - 2019/8

Y1 - 2019/8

KW - QUALITY-OF-LIFE

KW - INTRAABDOMINAL PRESSURE

KW - 1ST EVIDENCE

KW - CANCER

KW - PHARMACOKINETICS

KW - CARCINOMATOSIS

KW - SAFETY

KW - CLASSIFICATION

KW - QUESTIONNAIRE

KW - PENETRATION

U2 - 10.1136/bmjopen-2019-030408

DO - 10.1136/bmjopen-2019-030408

M3 - Article

VL - 9

SP - 1

EP - 10

JO - BMJ Open

JF - BMJ Open

SN - 2044-6055

IS - 7

M1 - 030408

ER -

Rovers KP, Lurvink RJ, Wassenaar ECE, Kootstra TJM, Scholten HJ, Tajzai R et al. Repetitive electrostatic pressurised intraperitoneal aerosol chemotherapy (ePIPAC) with oxaliplatin as a palliative monotherapy for isolated unresectable colorectal peritoneal metastases: protocol of a Dutch, multicentre, open-label, single-arm, phase II study (CRC-PIPAC). BMJ Open. 2019 Aug;9(7):1-10. 030408. https://doi.org/10.1136/bmjopen-2019-030408