TY - JOUR
T1 - Reflecting on a decade of the international consensus on ANA patterns (ICAP)
T2 - Accomplishments and challenges from the perspective of the 7th ICAP workshop
AU - Andrade, Luis E C
AU - Klotz, Werner
AU - Herold, Manfred
AU - Musset, Lucile
AU - Damoiseaux, Jan
AU - Infantino, Maria
AU - Carballo, Orlando G
AU - Choi, May
AU - von Mühlen, Carlos A
AU - La Torre, Ignacio Garcia-De
AU - Satoh, Minoru
AU - Francescantonio, Paulo L C
AU - Mimori, Tsuneyo
AU - Conrad, Karsten
AU - de Melo Cruvinel, Wilson
AU - Chan, Edward K L
AU - Fritzler, Marvin J
PY - 2024/9
Y1 - 2024/9
N2 - The International Consensus on ANA Patterns (ICAP) is an ongoing international initiative dedicated to harmonizing technical and interpretation aspects of the HEp-2 IFA test. Comprised of internationally recognized experts in autoimmunity and HEp-2 IFA testing, ICAP has operated for the last 10 years by promoting accurate reading, interpretation, and reporting of HEp-2 IFA images by professionals involved in various areas related to autoimmune diseases, such as clinical diagnostic laboratories, academic research, IVD industry, and patient care. ICAP operates through continuous information exchange with the international community and encourages the participation of younger experts from all over the world. The 7th ICAP workshop has addressed several aspects that originated from this interaction with the international community and has effectively established objective goals and tasks to be delivered over the next two years. Some of these are outlined in this article, including the planning of three audio-visual educational modules to be posted at the www.anapattern.org website, the classification of two novel HEp-2 IFA patterns, the implementation of a project dedicated to continuously updating the information on the clinical and immunologic relevance of the HEp-2 IFA patterns, and the launch of two additional branches of the HEp-2 Clinical and Immunological (HEp-2 CIC) project.
AB - The International Consensus on ANA Patterns (ICAP) is an ongoing international initiative dedicated to harmonizing technical and interpretation aspects of the HEp-2 IFA test. Comprised of internationally recognized experts in autoimmunity and HEp-2 IFA testing, ICAP has operated for the last 10 years by promoting accurate reading, interpretation, and reporting of HEp-2 IFA images by professionals involved in various areas related to autoimmune diseases, such as clinical diagnostic laboratories, academic research, IVD industry, and patient care. ICAP operates through continuous information exchange with the international community and encourages the participation of younger experts from all over the world. The 7th ICAP workshop has addressed several aspects that originated from this interaction with the international community and has effectively established objective goals and tasks to be delivered over the next two years. Some of these are outlined in this article, including the planning of three audio-visual educational modules to be posted at the www.anapattern.org website, the classification of two novel HEp-2 IFA patterns, the implementation of a project dedicated to continuously updating the information on the clinical and immunologic relevance of the HEp-2 IFA patterns, and the launch of two additional branches of the HEp-2 Clinical and Immunological (HEp-2 CIC) project.
KW - Anti-cell antibodies
KW - Antinuclear antibodies
KW - Autoantibodies
KW - Autoimmunity laboratory testing
KW - HEp-2 cell indirect immunofluorescence
KW - Systemic autoimmune diseases
U2 - 10.1016/j.autrev.2024.103608
DO - 10.1016/j.autrev.2024.103608
M3 - (Systematic) Review article
SN - 1568-9972
VL - 23
JO - Autoimmunity Reviews
JF - Autoimmunity Reviews
IS - 9
M1 - 103608
ER -