Reduction in extrapulmonary tuberculosis in context of antiretroviral therapy scale-up in rural South Africa

J. C. Hoogendoorn; L. Ranoto; N. Muditambi; J. Railton; M. Maswanganyi; H. E. Struthers; J. A. Mcintyre; R. P. H. Peters

doi:10.1017/S095026881700156X

Reduction in extrapulmonary tuberculosis in context of antiretroviral therapy scale-up in rural South Africa

J. C. Hoogendoorn, L. Ranoto, N. Muditambi, J. Railton, M. Maswanganyi, H. E. Struthers, J. A. Mcintyre, R. P. H. Peters^*

^*Corresponding author for this work

Research output: Contribution to journal › Article › Academic › peer-review

Abstract

Scale-up of antiretroviral therapy (ART) for human immunodeficiency virus (HIV) infection has reduced the incidence of pulmonary tuberculosis (PTB) in South Africa. Despite the strong association of HIV infection with extrapulmonary tuberculosis (EPTB), the effect of ART on the epidemiology of EPTB remains undocumented. We conducted a retrospective record review of patients initiated on treatment for EPTB in 2009 (ART coverage

Original language	English
Pages (from-to)	2500-2509
Number of pages	10
Journal	Epidemiology and Infection
Volume	145
Issue number	12
DOIs	https://doi.org/10.1017/S095026881700156X
Publication status	Published - Sept 2017

Keywords

Antiretroviral therapy
extrapulmonary tuberculosis
human immunodeficiency virus
pulmonary tuberculosis
rural South Africa
MILIARY TUBERCULOSIS
HIV-INFECTION
RISK-FACTORS
MORTALITY
BURDEN
TRENDS
EPIDEMIOLOGY
MANAGEMENT
COHORT
BRAZIL

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title = "Reduction in extrapulmonary tuberculosis in context of antiretroviral therapy scale-up in rural South Africa",

abstract = "Scale-up of antiretroviral therapy (ART) for human immunodeficiency virus (HIV) infection has reduced the incidence of pulmonary tuberculosis (PTB) in South Africa. Despite the strong association of HIV infection with extrapulmonary tuberculosis (EPTB), the effect of ART on the epidemiology of EPTB remains undocumented. We conducted a retrospective record review of patients initiated on treatment for EPTB in 2009 (ART coverage",

keywords = "Antiretroviral therapy, extrapulmonary tuberculosis, human immunodeficiency virus, pulmonary tuberculosis, rural South Africa, MILIARY TUBERCULOSIS, HIV-INFECTION, RISK-FACTORS, MORTALITY, BURDEN, TRENDS, EPIDEMIOLOGY, MANAGEMENT, COHORT, BRAZIL",

author = "Hoogendoorn, {J. C.} and L. Ranoto and N. Muditambi and J. Railton and M. Maswanganyi and Struthers, {H. E.} and Mcintyre, {J. A.} and Peters, {R. P. H.}",

year = "2017",

month = sep,

doi = "10.1017/S095026881700156X",

language = "English",

volume = "145",

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journal = "Epidemiology and Infection",

issn = "0950-2688",

publisher = "Cambridge University Press",

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TY - JOUR

T1 - Reduction in extrapulmonary tuberculosis in context of antiretroviral therapy scale-up in rural South Africa

AU - Hoogendoorn, J. C.

AU - Ranoto, L.

AU - Muditambi, N.

AU - Railton, J.

AU - Maswanganyi, M.

AU - Struthers, H. E.

AU - Mcintyre, J. A.

AU - Peters, R. P. H.

PY - 2017/9

Y1 - 2017/9

N2 - Scale-up of antiretroviral therapy (ART) for human immunodeficiency virus (HIV) infection has reduced the incidence of pulmonary tuberculosis (PTB) in South Africa. Despite the strong association of HIV infection with extrapulmonary tuberculosis (EPTB), the effect of ART on the epidemiology of EPTB remains undocumented. We conducted a retrospective record review of patients initiated on treatment for EPTB in 2009 (ART coverage

AB - Scale-up of antiretroviral therapy (ART) for human immunodeficiency virus (HIV) infection has reduced the incidence of pulmonary tuberculosis (PTB) in South Africa. Despite the strong association of HIV infection with extrapulmonary tuberculosis (EPTB), the effect of ART on the epidemiology of EPTB remains undocumented. We conducted a retrospective record review of patients initiated on treatment for EPTB in 2009 (ART coverage

KW - Antiretroviral therapy

KW - extrapulmonary tuberculosis

KW - human immunodeficiency virus

KW - pulmonary tuberculosis

KW - rural South Africa

KW - MILIARY TUBERCULOSIS

KW - HIV-INFECTION

KW - RISK-FACTORS

KW - MORTALITY

KW - BURDEN

KW - TRENDS

KW - EPIDEMIOLOGY

KW - MANAGEMENT

KW - COHORT

KW - BRAZIL

U2 - 10.1017/S095026881700156X

DO - 10.1017/S095026881700156X

M3 - Article

C2 - 28748775

SN - 0950-2688

VL - 145

SP - 2500

EP - 2509

JO - Epidemiology and Infection

JF - Epidemiology and Infection

IS - 12

ER -

Reduction in extrapulmonary tuberculosis in context of antiretroviral therapy scale-up in rural South Africa

Abstract

Keywords

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