Reduced delta power and synchrony and increased gamma power during the P3 time window in schizophrenia

Franc C. L. Donkers*, Zoe A. Englander, Paul H. E. Tiesinga, Katherine M. Cleary, Hongbin Gu, Aysenil Belger

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

10 Citations (Web of Science)

Abstract

Event-related potential studies in schizophrenia have demonstrated amplitude reduction of the P3 in oddball tasks. The P3 has been linked to attention and memory brain functions.In 24 schizophrenia patients and 28 control subjects, wavelet transform was used to reveal event-related modulations of the EEG signal during target trials in delta, theta, alpha, beta, and gamma frequency bands.Patients showed reductions in P3 amplitude accompanied by reduced low frequency delta-theta and increased beta-gamma band EEG activity.These results indicate abnormalities in the synchronization and/or efficiency of neural processes involved in memory and attention networks in schizophrenia.? 2013
Original languageEnglish
Pages (from-to)266-268
JournalSchizophrenia Research
Volume150
Issue number1
DOIs
Publication statusPublished - Oct 2013
Externally publishedYes

Keywords

  • Schizophrenia
  • Wavelet analysis
  • Time-frequency analysis
  • Delta frequency band
  • Theta frequency band
  • Gamma frequency band
  • P3

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