Redo surgery for neurogenic thoracic outlet syndrome is useful

INTRODUCTION: Surgery for Neurogenic Thoracic Outlet Syndrome (NTOS) has shown good outcome in numerous case series. However, 5-30% of patients will have persistent or recurrent symptoms, caused by incomplete first rib resection, reattachment of residual scalene muscle, fibrous scarring around the brachial plexus or a wrong NTOS diagnosis. In patients with a sound diagnosis of recurrent or persisting NTOS, not responding to conservative measures, a secondary procedure can be considered. We report the results of redo thoracic outlet decompression surgery through the supraclavicular approach (SC-REDO-TOD) for persistent or recurrent NTOS.

METHODS: A retrospective review of a prospective database was performed. Every patient referred from September 2016 until January 2020 was eligible for inclusion. In a SC-REDO-TOD we perform complete (cartilage-cartilage) resection of the first rib, any bony and fibrous anomalies, complete anterior and middle scalenectomy and complete neurolysis of the brachial plexus (= complete anatomical decompression of the brachial plexus). Clinical outcomes were assessed by questionnaires including the DASH (Disability of Arm, Shoulder and Hand), CBSQ (Cervico-Brachial Symptoms Questionnaire) and TOS disability scale.

RESULTS: In total, 45 patients had a SC-REDO-TOD. The median duration of hospital admission after SC-REDO-TOD was 1.41 days (IQR 1.00). In total 30/45 (66.66%) patients had recurrent NTOS and 15/45 (33.33%) patients had persisting NTOS. Postoperative complications were seen in 8 (18.18%) patients. 1 Patient had postoperative complications with permanent impairment (Horner syndrome). 7 Patients had postoperative complications with full recovery (3 patients had a chylous leakage which was treated with a median-chain triglycerides diet for 6 weeks, 3 patients had transient phrenic nerve palsy with full recovery < 6 weeks, 1 patient had a discrete Horner syndrome which resolved in 6 weeks). The median time of follow-up was 19.50 months (interquartile range (IQR) 14.00) and the response rate to the questionnaires was 91.11% at 6 months and 64.44% at 12 months. We found a positive and statistically significant difference for DASH score, CBSQ score and TOS Disability Scale score comparing scores for all patients. (DASH score: p<0.001; CBSQ score: p<0.001; TOS Disability Scale: p<0.001). Patients with first rib remnants showed a significant better response (lower DASH, CBSQ and TOS Disability Scale scores) compared to patients without first rib remnants (DASH score: p=0.004; CBSQ score: p<=0.014; TOS Disability Scale: p=0.009).

CONCLUSION: SC-REDO-TOD after a previous NTOS surgery shows good results with a low risk of permanent impairment. NTOS patients with first rib remnants after primary surgery seem to benefit the most from REDO surgery.