Recently Registered Midazolam Doses for Preterm Neonates Do Not Lead to Equal Exposure: A Population Pharmacokinetic Model

Swantje Voller; Robert B. Flint; Fouzi Beggah; Irwin Reiss; Peter Andriessen; Luc J. Zimmermann; John N. van den Anker; Kian D. Liem; Birgit C. P. Koch; Saskia de Wildt; Catherijne A. J. Knibbe; Sinno H. P. Simons

doi:10.1002/jcph.1429

Recently Registered Midazolam Doses for Preterm Neonates Do Not Lead to Equal Exposure: A Population Pharmacokinetic Model

Swantje Voller^*, Robert B. Flint, Fouzi Beggah, Irwin Reiss, Peter Andriessen, Luc J. Zimmermann, John N. van den Anker, Kian D. Liem, Birgit C. P. Koch, Saskia de Wildt, Catherijne A. J. Knibbe, Sinno H. P. Simons

^*Corresponding author for this work

Research output: Contribution to journal › Article › Academic › peer-review

Original language	English
Pages (from-to)	1300-1308
Number of pages	9
Journal	Journal of Clinical Pharmacology
Volume	59
Issue number	10
DOIs	https://doi.org/10.1002/jcph.1429
Publication status	Published - Oct 2019

Keywords

drug metabolism
fetal medicine
neonatology
pharmacokinetics
pharmacometrics
population pharmacokinetics
ORAL MIDAZOLAM
METABOLISM
SEDATION
INFANTS
LIVER

Access to Document

10.1002/jcph.1429

Cite this

Voller, S., Flint, R. B., Beggah, F., Reiss, I., Andriessen, P., Zimmermann, L. J., van den Anker, J. N., Liem, K. D., Koch, B. C. P., de Wildt, S., Knibbe, C. A. J., & Simons, S. H. P. (2019). Recently Registered Midazolam Doses for Preterm Neonates Do Not Lead to Equal Exposure: A Population Pharmacokinetic Model. Journal of Clinical Pharmacology, 59(10), 1300-1308. https://doi.org/10.1002/jcph.1429

Voller, Swantje ; Flint, Robert B. ; Beggah, Fouzi ; Reiss, Irwin ; Andriessen, Peter ; Zimmermann, Luc J. ; van den Anker, John N. ; Liem, Kian D. ; Koch, Birgit C. P. ; de Wildt, Saskia ; Knibbe, Catherijne A. J. ; Simons, Sinno H. P. / Recently Registered Midazolam Doses for Preterm Neonates Do Not Lead to Equal Exposure : A Population Pharmacokinetic Model. In: Journal of Clinical Pharmacology. 2019 ; Vol. 59, No. 10. pp. 1300-1308.

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title = "Recently Registered Midazolam Doses for Preterm Neonates Do Not Lead to Equal Exposure: A Population Pharmacokinetic Model",

keywords = "drug metabolism, fetal medicine, neonatology, pharmacokinetics, pharmacometrics, population pharmacokinetics, ORAL MIDAZOLAM, METABOLISM, SEDATION, INFANTS, LIVER",

author = "Swantje Voller and Flint, {Robert B.} and Fouzi Beggah and Irwin Reiss and Peter Andriessen and Zimmermann, {Luc J.} and {van den Anker}, {John N.} and Liem, {Kian D.} and Koch, {Birgit C. P.} and {de Wildt}, Saskia and Knibbe, {Catherijne A. J.} and Simons, {Sinno H. P.}",

year = "2019",

month = oct,

doi = "10.1002/jcph.1429",

language = "English",

volume = "59",

pages = "1300--1308",

journal = "Journal of Clinical Pharmacology",

issn = "0091-2700",

publisher = "Wiley",

number = "10",

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Voller, S, Flint, RB, Beggah, F, Reiss, I, Andriessen, P, Zimmermann, LJ, van den Anker, JN, Liem, KD, Koch, BCP, de Wildt, S, Knibbe, CAJ & Simons, SHP 2019, 'Recently Registered Midazolam Doses for Preterm Neonates Do Not Lead to Equal Exposure: A Population Pharmacokinetic Model', Journal of Clinical Pharmacology, vol. 59, no. 10, pp. 1300-1308. https://doi.org/10.1002/jcph.1429

Recently Registered Midazolam Doses for Preterm Neonates Do Not Lead to Equal Exposure : A Population Pharmacokinetic Model. / Voller, Swantje; Flint, Robert B.; Beggah, Fouzi; Reiss, Irwin; Andriessen, Peter; Zimmermann, Luc J.; van den Anker, John N.; Liem, Kian D.; Koch, Birgit C. P.; de Wildt, Saskia; Knibbe, Catherijne A. J.; Simons, Sinno H. P.

In: Journal of Clinical Pharmacology, Vol. 59, No. 10, 10.2019, p. 1300-1308.

Research output: Contribution to journal › Article › Academic › peer-review

TY - JOUR

T1 - Recently Registered Midazolam Doses for Preterm Neonates Do Not Lead to Equal Exposure

T2 - A Population Pharmacokinetic Model

AU - Voller, Swantje

AU - Flint, Robert B.

AU - Beggah, Fouzi

AU - Reiss, Irwin

AU - Andriessen, Peter

AU - Zimmermann, Luc J.

AU - van den Anker, John N.

AU - Liem, Kian D.

AU - Koch, Birgit C. P.

AU - de Wildt, Saskia

AU - Knibbe, Catherijne A. J.

AU - Simons, Sinno H. P.

PY - 2019/10

Y1 - 2019/10

KW - drug metabolism

KW - fetal medicine

KW - neonatology

KW - pharmacokinetics

KW - pharmacometrics

KW - population pharmacokinetics

KW - ORAL MIDAZOLAM

KW - METABOLISM

KW - SEDATION

KW - INFANTS

KW - LIVER

U2 - 10.1002/jcph.1429

DO - 10.1002/jcph.1429

M3 - Article

VL - 59

SP - 1300

EP - 1308

JO - Journal of Clinical Pharmacology

JF - Journal of Clinical Pharmacology

SN - 0091-2700

IS - 10

ER -