Real-world costs of chronic lymphocytic leukaemia in the Netherlands

K. M. Holtzer-Goor; C. A M Bouwmans-Frijters; M. R. Schaafsma; O. de Weerdt; P. Joosten; E. F M Posthuma; S. Wittebol; P. C. Huijgens; E. J M Mattijssen; G. Vreugdenhil; H. Visser; W. G. Peters; Z. Erjavec; P. W. Wijermans; S. M G J Daenen; K. G. van der Hem; M. H J van Oers; C. A Uyl de Groot

doi:10.1016/j.leukres.2013.10.029

Real-world costs of chronic lymphocytic leukaemia in the Netherlands

K. M. Holtzer-Goor^*, C. A M Bouwmans-Frijters, M. R. Schaafsma, O. de Weerdt, P. Joosten, E. F M Posthuma, S. Wittebol, P. C. Huijgens, E. J M Mattijssen, G. Vreugdenhil, H. Visser, W. G. Peters, Z. Erjavec, P. W. Wijermans, S. M G J Daenen, K. G. van der Hem, M. H J van Oers, C. A Uyl de Groot

^*Corresponding author for this work

Research output: Contribution to journal › Article › Academic › peer-review

Abstract

We performed a comprehensive cost calculation identifying the main cost drivers of treatment of chronic lymphocytic leukaemia in daily practice. In our observational study 160 patient charts were reviewed repeatedly to assess the treatment strategies from diagnosis till the study end. Ninety-seven patients (61%) received >= 1 treatment lines during an average follow-up time of 6.4 years. The average total costs per patient were (sic)41,417 ((sic)539 per month). The costs varied considerably between treatment groups and between treatment lines. Although patients were treated with expensive chemo(immuno-)therapy, the main cost driver was inpatient days for other reasons than administration of chemo(immuno-)therapy. (C) 2013 Elsevier Ltd. All rights reserved.

Original language	English
Pages (from-to)	84-90
Number of pages	7
Journal	Leukemia Research
Volume	38
Issue number	1
DOIs	https://doi.org/10.1016/j.leukres.2013.10.029
Publication status	Published - Jan 2014

Keywords

Chronic lymphocytic leukaemia
Cost of illness
Costs
Observational study
Outcomes research
Real-world

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http://www.mendeley.com/research/realworld-costs-chronic-lymphocytic-leukaemia-netherlands

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Holtzer-Goor, K. M., Bouwmans-Frijters, C. A. M., Schaafsma, M. R., de Weerdt, O., Joosten, P., Posthuma, E. F. M., Wittebol, S., Huijgens, P. C., Mattijssen, E. J. M., Vreugdenhil, G., Visser, H., Peters, W. G., Erjavec, Z., Wijermans, P. W., Daenen, S. M. G. J., van der Hem, K. G., van Oers, M. H. J., & Groot, C. A. U. D. (2014). Real-world costs of chronic lymphocytic leukaemia in the Netherlands. Leukemia Research, 38(1), 84-90. https://doi.org/10.1016/j.leukres.2013.10.029

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abstract = "We performed a comprehensive cost calculation identifying the main cost drivers of treatment of chronic lymphocytic leukaemia in daily practice. In our observational study 160 patient charts were reviewed repeatedly to assess the treatment strategies from diagnosis till the study end. Ninety-seven patients (61%) received >= 1 treatment lines during an average follow-up time of 6.4 years. The average total costs per patient were (sic)41,417 ((sic)539 per month). The costs varied considerably between treatment groups and between treatment lines. Although patients were treated with expensive chemo(immuno-)therapy, the main cost driver was inpatient days for other reasons than administration of chemo(immuno-)therapy. (C) 2013 Elsevier Ltd. All rights reserved.",

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Holtzer-Goor, KM, Bouwmans-Frijters, CAM, Schaafsma, MR, de Weerdt, O, Joosten, P, Posthuma, EFM, Wittebol, S, Huijgens, PC, Mattijssen, EJM, Vreugdenhil, G, Visser, H, Peters, WG, Erjavec, Z, Wijermans, PW, Daenen, SMGJ, van der Hem, KG, van Oers, MHJ & Groot, CAUD 2014, 'Real-world costs of chronic lymphocytic leukaemia in the Netherlands', Leukemia Research, vol. 38, no. 1, pp. 84-90. https://doi.org/10.1016/j.leukres.2013.10.029

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AU - Holtzer-Goor, K. M.

AU - Bouwmans-Frijters, C. A M

AU - Schaafsma, M. R.

AU - de Weerdt, O.

AU - Joosten, P.

AU - Posthuma, E. F M

AU - Wittebol, S.

AU - Huijgens, P. C.

AU - Mattijssen, E. J M

AU - Vreugdenhil, G.

AU - Visser, H.

AU - Peters, W. G.

AU - Erjavec, Z.

AU - Wijermans, P. W.

AU - Daenen, S. M G J

AU - van der Hem, K. G.

AU - van Oers, M. H J

AU - Groot, C. A Uyl de

N1 - No ISBN available. ISSN is 0145-2126.

PY - 2014/1

Y1 - 2014/1

N2 - We performed a comprehensive cost calculation identifying the main cost drivers of treatment of chronic lymphocytic leukaemia in daily practice. In our observational study 160 patient charts were reviewed repeatedly to assess the treatment strategies from diagnosis till the study end. Ninety-seven patients (61%) received >= 1 treatment lines during an average follow-up time of 6.4 years. The average total costs per patient were (sic)41,417 ((sic)539 per month). The costs varied considerably between treatment groups and between treatment lines. Although patients were treated with expensive chemo(immuno-)therapy, the main cost driver was inpatient days for other reasons than administration of chemo(immuno-)therapy. (C) 2013 Elsevier Ltd. All rights reserved.

AB - We performed a comprehensive cost calculation identifying the main cost drivers of treatment of chronic lymphocytic leukaemia in daily practice. In our observational study 160 patient charts were reviewed repeatedly to assess the treatment strategies from diagnosis till the study end. Ninety-seven patients (61%) received >= 1 treatment lines during an average follow-up time of 6.4 years. The average total costs per patient were (sic)41,417 ((sic)539 per month). The costs varied considerably between treatment groups and between treatment lines. Although patients were treated with expensive chemo(immuno-)therapy, the main cost driver was inpatient days for other reasons than administration of chemo(immuno-)therapy. (C) 2013 Elsevier Ltd. All rights reserved.

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KW - Cost of illness

KW - Costs

KW - Observational study

KW - Outcomes research

KW - Real-world

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SN - 0145-2126

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SP - 84

EP - 90

JO - Leukemia Research

JF - Leukemia Research

IS - 1

ER -

Real-world costs of chronic lymphocytic leukaemia in the Netherlands

Abstract

Keywords

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