Real-world costs of chronic lymphocytic leukaemia in the Netherlands

K. M. Holtzer-Goor*, C. A M Bouwmans-Frijters, M. R. Schaafsma, O. de Weerdt, P. Joosten, E. F M Posthuma, S. Wittebol, P. C. Huijgens, E. J M Mattijssen, G. Vreugdenhil, H. Visser, W. G. Peters, Z. Erjavec, P. W. Wijermans, S. M G J Daenen, K. G. van der Hem, M. H J van Oers, C. A Uyl de Groot

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review


We performed a comprehensive cost calculation identifying the main cost drivers of treatment of chronic lymphocytic leukaemia in daily practice. In our observational study 160 patient charts were reviewed repeatedly to assess the treatment strategies from diagnosis till the study end. Ninety-seven patients (61%) received ???1 treatment lines during an average follow-up time of 6.4 years. The average total costs per patient were ???41,417 (???539 per month). The costs varied considerably between treatment groups and between treatment lines. Although patients were treated with expensive chemo(immuno-)therapy, the main cost driver was inpatient days for other reasons than administration of chemo(immuno-)therapy. ?? 2013 Elsevier Ltd.
Original languageEnglish
Pages (from-to)84-90
Number of pages7
JournalLeukemia Research
Issue number1
Publication statusPublished - Jan 2014


  • Chronic lymphocytic leukaemia
  • Cost of illness
  • Costs
  • Observational study
  • Outcomes research
  • Real-world

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