Reactive Oxygen-Forming Nox5 Links Vascular Smooth Muscle Cell Phenotypic Switching and Extracellular Vesicle-Mediated Vascular Calcification

Malgorzata Furmanik, Martijn Chatrou, Rick van Gorp, Asim Akbulut, Brecht Willems, Harald Schmidt, Guillaume van Eys, Marie-Luce Bochaton-Piallat, Diane Proudfoot, Erik Biessen, Ulf Hedin, Ljubica Perisic, Barend Mees, Catherine Shanahan, Chris Reutelingsperger, Leon Schurgers*

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

Original languageEnglish
Pages (from-to)911-927
Number of pages17
JournalCirculation Research
Volume127
Issue number7
DOIs
Publication statusPublished - 11 Sep 2020

Keywords

  • calcium
  • extracellular vesicles
  • NADPH oxidase 5
  • phenotype
  • vascular calcification
  • OXIDATIVE STRESS
  • MATRIX VESICLES
  • ARTERIAL CALCIFICATION
  • CALCIUM
  • MECHANISM
  • DIFFERENTIATION
  • OXIDASE
  • PHAGOCYTOSIS
  • EXPRESSION
  • APOPTOSIS

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