Random effects models for estimation of the probability and time to progression of a continuous biomarker

Tarylee Reddy; Geert Molenberghs; Liesbeth Bruckers; Edmund-Njeru Njagi; Marc Aerts; Geert Willem Schurink

doi:10.1002/pst.1956

Random effects models for estimation of the probability and time to progression of a continuous biomarker

Tarylee Reddy^*, Geert Molenberghs, Liesbeth Bruckers, Edmund-Njeru Njagi, Marc Aerts, Geert Willem Schurink

^*Corresponding author for this work

Research output: Contribution to journal › Article › Academic › peer-review

Original language	English
Pages (from-to)	671-687
Number of pages	17
Journal	Pharmaceutical Statistics
Volume	18
Issue number	6
Early online date	15 Jul 2019
DOIs	https://doi.org/10.1002/pst.1956
Publication status	Published - Nov 2019

Keywords

persistence criteria
prediction
serial correlation
threshold
DISEASE PROGRESSION
LYMPHOCYTE COUNT
INFECTION
MORTALITY
INTERVALS

Access to Document

10.1002/pst.1956

Cite this

Reddy, T., Molenberghs, G., Bruckers, L., Njagi, E-N., Aerts, M., & Schurink, G. W. (2019). Random effects models for estimation of the probability and time to progression of a continuous biomarker. Pharmaceutical Statistics, 18(6), 671-687. https://doi.org/10.1002/pst.1956

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keywords = "persistence criteria, prediction, serial correlation, threshold, DISEASE PROGRESSION, LYMPHOCYTE COUNT, INFECTION, MORTALITY, INTERVALS",

author = "Tarylee Reddy and Geert Molenberghs and Liesbeth Bruckers and Edmund-Njeru Njagi and Marc Aerts and Schurink, {Geert Willem}",

year = "2019",

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language = "English",

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journal = "Pharmaceutical Statistics",

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Random effects models for estimation of the probability and time to progression of a continuous biomarker. / Reddy, Tarylee; Molenberghs, Geert; Bruckers, Liesbeth; Njagi, Edmund-Njeru; Aerts, Marc; Schurink, Geert Willem.

In: Pharmaceutical Statistics, Vol. 18, No. 6, 11.2019, p. 671-687.

Research output: Contribution to journal › Article › Academic › peer-review

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T1 - Random effects models for estimation of the probability and time to progression of a continuous biomarker

AU - Reddy, Tarylee

AU - Molenberghs, Geert

AU - Bruckers, Liesbeth

AU - Njagi, Edmund-Njeru

AU - Aerts, Marc

AU - Schurink, Geert Willem

PY - 2019/11

Y1 - 2019/11

KW - persistence criteria

KW - prediction

KW - serial correlation

KW - threshold

KW - DISEASE PROGRESSION

KW - LYMPHOCYTE COUNT

KW - INFECTION

KW - MORTALITY

KW - INTERVALS

U2 - 10.1002/pst.1956

DO - 10.1002/pst.1956

M3 - Article

VL - 18

SP - 671

EP - 687

JO - Pharmaceutical Statistics

JF - Pharmaceutical Statistics

SN - 1539-1604

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ER -