Quantification of total and unbound cefuroxime in plasma by ultra-performance liquid chromatography tandem mass spectrometry in a cohort of critically ill patients with hypoalbuminemia and renal failure

Joost J. van Raaij, Noortje J. D. Mabelis, Kimberly N. Shudofsky, Sjoerd D. Meenks, Jos L. M. L. le Noble, Paddy K. C. Janssen*

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

Original languageEnglish
Article number23100
Number of pages7
JournalJournal of Clinical Laboratory Analysis
Volume34
Issue number3
Early online date30 Nov 2019
DOIs
Publication statusPublished - Mar 2020

Keywords

  • cefuroxime
  • hypoalbuminemia
  • intensive care unit
  • therapeutic drug monitoring
  • unbound concentration
  • PROTEIN-BINDING

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