Quality of life more impaired in younger than in older diffuse large B cell lymphoma survivors compared to a normative population: a study from the population-based PROFILES registry

M. W. M. van der Poel*, S. Oerlemans, H. C. Schouten, F. Mols, J. F. M. Pruijt, H. Maas, L. V. van de Poll-Franse

*Corresponding author for this work

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The objective of this study was to compare health-related quality of life (HRQOL) between diffuse large B cell lymphoma (DLBCL) survivors of different age categories (18-59/60-75/76-85?years) and to compare their HRQOL with an age- and sex-matched normative population. The population-based Eindhoven Cancer Registry was used to select all patients diagnosed with DLBCL from 1999 to 2010. Patients (n?=?363) were invited to complete the European Organization for Research and Treatment of Cancer Quality of Life Questionnaire-Core 30 (EORTC QLQ-C30) questionnaire, and 307 survivors responded (85?%). Data from an age- and sex-matched normative population (n?=?596) were used for comparison. DLBCL survivors aged 18-59?years scored better on physical functioning, quality of life, appetite loss and constipation than survivors of 76-85?years old (all p?
Original languageEnglish
Pages (from-to)811-819
JournalAnnals of Hematology
Issue number5
Publication statusPublished - May 2014


  • Diffuse large B cell lymphoma
  • Quality of life
  • Elderly
  • Population based

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