Quality of Life Changes in Filipino Cancer Patients from Baseline to One Year after Diagnosis: a Country-specific Analysis of the ACTION Study

Corazon A. Ngelangel, Hilton Lam, Adovich Sarmiento Rivera, Merel Kimman, Irisyl Orolfo-Real, Soledad L. Balete

Research output: Contribution to journalArticleAcademicpeer-review


Background: Health-related quality of life is an important aspect of cancer research. Studies in the Philippines documenting this among survivors are limited in scope and number.

Objective: To document quality of life indicators of Filipino cancer survivors starting at 12 months from diagnosis and identify predictors of these changes.

Methods: The ACTION study is a prospective longitudinal study examining the economic and health impact of cancer in the Southeast Asian Region. A country-specific analysis for Filipino patients was conducted.

Results: Of the 909 Filipinos included in the study, 462 survived month 12 and had health-related quality of life (HRQoL) data. HRQoL data showed significant improvement from baseline (0.73, SD: 0.15) to month 12 (0.79, SD: 0.24) as measured by the EQ-5D weight score. Similar trends were seen in the EQ5D VAS Scores and the QLQ30 Global function scores. There was, however, an increase in the proportion of respondents experiencing significant problems related to EQ5D domains by month 12. Data disaggregated according to cancer type showed a decrease in QLQ30 GF scores from baseline to month 12 for all types except breast cancer. Individuals at risk of anxiety and depression increased from 15.37% to 25.54% and 18.83% to 32.25%, respectively. Predictors of worsening HRQOL include experiencing economic hardship, progression of disease, and higher stage at baseline.

Conclusion: HRQOL scores were found to increase despite experiencing more difficulties in function among Filipino cancer survivors one year after diagnosis.
Original languageEnglish
Pages (from-to)1-10
Number of pages10
JournalPhilippine Journal of Health Research and Development
Issue number1
Publication statusPublished - 2017

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