TY - JOUR
T1 - Quality of Life after Brain Injury (QOLIBRI): Scale Validity and Correlates of Quality of Life
AU - von Steinbüchel, Nicole
AU - Wilson, Lindsay
AU - Gibbons, Henning
AU - Hawthorne, Graeme
AU - Hoefer, Stefan
AU - Schmidt, Silke
AU - Bullinger, Monika
AU - Maas, Andrew
AU - Neugebauer, Edmund
AU - Powell, Jane
AU - von Wild, Klaus
AU - Zitnay, George
AU - Bakx, Wilbert
AU - Christensen, Anne-Lise
AU - Koskinen, Sanna
AU - Formisano, Rita
AU - Saarajuri, Jana
AU - Sasse, Nadine
AU - Truelle, Jean-Luc
PY - 2010/7
Y1 - 2010/7
N2 - The QOLIBRI (Quality of Life after Brain Injury) is a novel health-related quality-of-life (HRQoL) instrument specifically developed for traumatic brain injury (TBI). It provides a profile of HRQoL in six domains together with an overall score. Scale validity and factors associated with HRQoL were investigated in a multi-center international study. A total of 795 adults with brain injury were studied from 3 months to 15 years post-injury. The majority of participants (58%) had severe injuries as assessed by 24-h worst Glasgow Coma Scale (GCS) score. Systematic relationships were observed between the QOLIBRI and the Glasgow Outcome Scale-Extended (GOSE), Hospital Anxiety and Depression Scale (HADS), and SF-36. Within each scale patients with disability reported having low HRQoL in two to three times as many areas as those who had made a good recovery. The main correlates of the total QOLIBRI score were emotional state (HADS depression and anxiety), functional status (amount of help needed and outcome on the GOSE), and comorbid health conditions. Together these five variables accounted for 58% of the variance in total QOLIBRI scores. The QOLIBRI is the first tool developed to assess disease-specific HRQoL in brain injury, and it contains novel information not given by other currently available assessments.
AB - The QOLIBRI (Quality of Life after Brain Injury) is a novel health-related quality-of-life (HRQoL) instrument specifically developed for traumatic brain injury (TBI). It provides a profile of HRQoL in six domains together with an overall score. Scale validity and factors associated with HRQoL were investigated in a multi-center international study. A total of 795 adults with brain injury were studied from 3 months to 15 years post-injury. The majority of participants (58%) had severe injuries as assessed by 24-h worst Glasgow Coma Scale (GCS) score. Systematic relationships were observed between the QOLIBRI and the Glasgow Outcome Scale-Extended (GOSE), Hospital Anxiety and Depression Scale (HADS), and SF-36. Within each scale patients with disability reported having low HRQoL in two to three times as many areas as those who had made a good recovery. The main correlates of the total QOLIBRI score were emotional state (HADS depression and anxiety), functional status (amount of help needed and outcome on the GOSE), and comorbid health conditions. Together these five variables accounted for 58% of the variance in total QOLIBRI scores. The QOLIBRI is the first tool developed to assess disease-specific HRQoL in brain injury, and it contains novel information not given by other currently available assessments.
KW - health-related quality of life
KW - multi-national study
KW - outcome instrument
KW - traumatic brain injury
U2 - 10.1089/neu.2009.1077
DO - 10.1089/neu.2009.1077
M3 - Article
SN - 0897-7151
VL - 27
SP - 1157
EP - 1165
JO - Journal of Neurotrauma
JF - Journal of Neurotrauma
IS - 7
ER -