Prothrombin Loading of Vascular Smooth Muscle Cell-Derived Exosomes Regulates Coagulation and Calcification

Alexander N. Kapustin, Michael Schoppet, Leon J. Schurgers, Joanne L. Reynolds, Rosamund McNair, Alexander Heiss, Willi Jahnen-Dechent, Tilman M. Hackeng, Georg Schlieper, Paul Harrison, Catherine M. Shanahan*

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

Original languageEnglish
Pages (from-to)E22-E32
Number of pages11
JournalArteriosclerosis Thrombosis and Vascular Biology
Volume37
Issue number3
DOIs
Publication statusPublished - Mar 2017

Keywords

  • anticoagulants
  • exosomes
  • myocytes
  • smooth muscle
  • prothrombin
  • vascular calcification
  • MATRIX GLA PROTEIN
  • HUMAN ATHEROSCLEROTIC PLAQUES
  • FETUIN-MINERAL COMPLEX
  • TISSUE FACTOR
  • CARDIOVASCULAR CALCIFICATION
  • CALCIPROTEIN PARTICLES
  • EXTRACELLULAR CALCIUM
  • POTENTIAL MECHANISM
  • CHEMICAL SYNTHESIS
  • ENDOTHELIAL-CELLS

Cite this

Kapustin, A. N., Schoppet, M., Schurgers, L. J., Reynolds, J. L., McNair, R., Heiss, A., Jahnen-Dechent, W., Hackeng, T. M., Schlieper, G., Harrison, P., & Shanahan, C. M. (2017). Prothrombin Loading of Vascular Smooth Muscle Cell-Derived Exosomes Regulates Coagulation and Calcification. Arteriosclerosis Thrombosis and Vascular Biology, 37(3), E22-E32. https://doi.org/10.1161/ATVBAHA.116.308886