Protein, weight management, and satiety

D. Paddon Jones, E. Westman, R.D. Mattes, R.R. Wolfe, A. Astrup, M.S. Westerterp-Plantenga

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    Abstract

    Obesity, with its comorbidities such as metabolic syndrome and cardiovascular diseases, is a major public health concern. To address this problem, it is imperative to identify treatment interventions that target a variety of short- and long-term mechanisms. Although any dietary or lifestyle change must be personalized, controlled energy intake in association with a moderately elevated protein intake may represent an effective and practical weight-loss strategy. Potential beneficial outcomes associated with protein ingestion include the following: 1) increased satiety--protein generally increases satiety to a greater extent than carbohydrate or fat and may facilitate a reduction in energy consumption under ad libitum dietary conditions; 2) increased thermogenesis--higher-protein diets are associated with increased thermogenesis, which also influences satiety and augments energy expenditure (in the longer term, increased thermogenesis contributes to the relatively low-energy efficiency of protein); and 3) maintenance or accretion of fat-free mass--in some individuals, a moderately higher protein diet may provide a stimulatory effect on muscle protein anabolism, favoring the retention of lean muscle mass while improving metabolic profile. Nevertheless, any potential benefits associated with a moderately elevated protein intake must be evaluated in the light of customary dietary practices and individual variability.
    Original languageEnglish
    Pages (from-to)1558s-1561s
    JournalAmerican Journal of Clinical Nutrition
    Volume87
    Issue number5
    DOIs
    Publication statusPublished - 1 Jan 2008

    Cite this

    Paddon Jones, D., Westman, E., Mattes, R. D., Wolfe, R. R., Astrup, A., & Westerterp-Plantenga, M. S. (2008). Protein, weight management, and satiety. American Journal of Clinical Nutrition, 87(5), 1558s-1561s. https://doi.org/10.1093/ajcn/87.5.1558S