Protein kinase D increases maximal Ca2+-activated tension of cardiomyocyte contraction by phosphorylation of cMyBP-C-Ser(315)

Ellen Dirkx*, Olivier Cazorla, Robert W. Schwenk, Ilka Lorenzen-Schmidt, Sakthivel Sadayappan, Johan Van Lint, Lucie Carrier, Guillaume J. J. M. van Eys, Jan F. C. Glatz, Joost J. F. P. Luiken

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

Original languageEnglish
Pages (from-to)H323-H331
JournalAmerican Journal of Physiology-heart and Circulatory Physiology
Issue number3
Publication statusPublished - Aug 2012


  • cardiomyocyte contractility
  • calcium sensitivity
  • protein kinase A
  • phospho-cardiac myosin-binding protein C-serine-315

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