Protein farnesylation inhibitors cause donut-shaped cell nuclei attributable to a centrosome separation defect

Valerie L. R. M. Verstraeten, Lana A. Peckham, Michelle Olive, Brian C. Capell, Francis S. Collins, Elizabeth G. Nabel, Stephen G. Young, Loren G. Fong, Jan Lammerding

Research output: Contribution to journalArticleAcademicpeer-review

Original languageEnglish
Pages (from-to)4997-5002
JournalProceedings of the National Academy of Sciences of the United States of America
Volume108
Issue number12
DOIs
Publication statusPublished - 22 Mar 2011

Keywords

  • cell division
  • nuclear envelope
  • doughnut-shaped nuclei
  • antitumor

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