Protective role of c-Jun N-terminal kinase-2 (JNK2) in ibuprofen-induced acute liver injury

Miguel E. Zoubek, Marius M. Woitok, Svenja Sydor, Leonard J. Nelson, Lars P. Bechmann, Maria I. Lucena, Raul J. Andrade, Aalt Bast, Ger H. Koek, Christian Trautwein*, Francisco J. Cubero

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

Original languageEnglish
Pages (from-to)110-122
Number of pages13
JournalJournal of Pathology
Volume247
Issue number1
DOIs
Publication statusPublished - Jan 2019

Keywords

  • ibuprofen
  • toxicity
  • drug-induced liver injury (DILI)
  • JNK
  • liver failure
  • VANISHING BILE-DUCT
  • STEVENS-JOHNSON-SYNDROME
  • HEPATITIS
  • HEPATOTOXICITY
  • RESPIRATION
  • POPULATION
  • TOXICITY
  • MEDIATOR
  • NECROSIS
  • OUTCOMES

Cite this

Zoubek, M. E., Woitok, M. M., Sydor, S., Nelson, L. J., Bechmann, L. P., Lucena, M. I., Andrade, R. J., Bast, A., Koek, G. H., Trautwein, C., & Cubero, F. J. (2019). Protective role of c-Jun N-terminal kinase-2 (JNK2) in ibuprofen-induced acute liver injury. Journal of Pathology, 247(1), 110-122. https://doi.org/10.1002/path.5174