Protection against methylglyoxal-derived AGEs by regulation of glyoxalase 1 prevents retinal neuroglial and vasodegenerative pathology

A. K. Berner, O. Brouwers, R. Pringle, I. Klaassen, L. Colhoun, C. McVicar, S. Brockbank, J. W. Curry, T. Miyata, M. Brownlee, R. O. Schlingemann, C. Schalkwijk, A. W. Stitt

Research output: Contribution to journalArticleAcademicpeer-review

63 Citations (Scopus)
Original languageEnglish
Pages (from-to)845-854
JournalDiabetologia
Volume55
Issue number3
DOIs
Publication statusPublished - Mar 2012

Keywords

  • AGEs
  • Diabetic complications
  • Diabetic retinopathy
  • Glyoxalase 1
  • Methylglyoxal
  • Pathogenesis
  • Retina

Cite this

Berner, A. K., Brouwers, O., Pringle, R., Klaassen, I., Colhoun, L., McVicar, C., Brockbank, S., Curry, J. W., Miyata, T., Brownlee, M., Schlingemann, R. O., Schalkwijk, C., & Stitt, A. W. (2012). Protection against methylglyoxal-derived AGEs by regulation of glyoxalase 1 prevents retinal neuroglial and vasodegenerative pathology. Diabetologia, 55(3), 845-854. https://doi.org/10.1007/s00125-011-2393-0