Pronounced between-subject and circadian variability in thymidylate synthase and dihydropyrimidine dehydrogenase enzyme activity in human volunteers

Bart A. W. Jacobs, Maarten J. Deenen, Dick Pluim, J. G. Coen van Hasselt, Martin D. Krahenbuhl, Robin M. J. M. van Geel, Niels de Vries, Hilde Rosing, Didier Meulendijks, Artur M. Burylo, Annemieke Cats, Jos H. Beijnen, Alwin D. R. Huitema, Jan H. M. Schellens*

*Corresponding author for this work

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Neuroscience

Pharmacology, Toxicology and Pharmaceutical Science