Promoter methylation of DNA damage repair (DDR) genes in human tumor entities: RBBP8/CtIP is almost exclusively methylated in bladder cancer

Jolein Mijnes, Juergen Veeck, Nadine T. Gaisa, Eduard Burghardt, Tim C. de Ruijter, Sonja Gostek, Edgar Dahl, David Pfister, Sebastian C. Schmid, Ruth Knuchel, Michael Rose

Research output: Contribution to journalArticleAcademicpeer-review

Original languageEnglish
Article number15
Number of pages20
JournalClinical epigenetics
Volume10
DOIs
Publication statusPublished - 6 Feb 2018

Keywords

  • RBBP8/CtIP
  • DNA repair
  • Bladder cancer/BLCA
  • Epigenetics
  • Infinium HumanMethylation450 BeadChip
  • Urine biomarker
  • PLATINUM-BASED CHEMOTHERAPY
  • HOMOLOGOUS RECOMBINATION REPAIR
  • OVARIAN-CANCER
  • BREAST-CANCER
  • END RESECTION
  • CELL-CYCLE
  • MICROSATELLITE INSTABILITY
  • EPIGENETIC INACTIVATION
  • PREDICTIVE BIOMARKER
  • UROTHELIAL CARCINOMA

Cite this

Mijnes, J., Veeck, J., Gaisa, N. T., Burghardt, E., de Ruijter, T. C., Gostek, S., Dahl, E., Pfister, D., Schmid, S. C., Knuchel, R., & Rose, M. (2018). Promoter methylation of DNA damage repair (DDR) genes in human tumor entities: RBBP8/CtIP is almost exclusively methylated in bladder cancer. Clinical epigenetics, 10, [15]. https://doi.org/10.1186/s13148-018-0447-6