Prognostic role of endocarditis in isolated tricuspid valve surgery. A propensity-weighted study

Michele Di Mauro, Marco Russo*, Guglielmo Saitto, Antonio Lio, Paolo Berretta, Maurizio Taramasso, Roberto Scrofani, Alessandro Della Corte, Sandro Sponga, Ernesto Greco, Matteo Saccocci, Antonio Calafiore, Giacomo Bianchi, Dror B Leviner, Andrea Biondi, Ugolino Livi, Erez Sharoni, Carlo De Vincentiis, Marco Di Eusanio, Carlo AntonaGiovanni Troise, Marco Solinas, Guenther Laufer, Francesco Musumeci, Martin Andreas

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

1 Citation (Web of Science)


OBJECTIVES: The role of the underlying etiology in isolated tricuspid valve surgery has not been investigated extensively in current literature. Aim of this study was to analyse outcomes of patients undergoing surgery due to endocarditis compared to other pathologies.

METHODS: The SURTRI study is a multicenter study enrolling adult patients who underwent isolated tricuspid valve surgery (n = 406, 55 ± 16 y.o.; 56% female) at 13 international sites. Propensity weighted analysis was performed to compare groups (IE group n = 107 vs Not-IE group n = 299).

RESULTS: No difference was found regarding the 30-day mortality (Group IE: 2.8% vs Group Not-IE = 6.8%; OR = 0.45) and major adverse events. Weighted cumulative incidence of cardiac death was significantly higher for patients with endocarditis (p = 0.01). The composite endpoint of cardiac death and reoperation at 6 years was reduced in the Group IE (63.2 ± 6.8% vs 78.9 ± 3.1%; p = 0.022). Repair strategy resulted in an increased late survival even in IE cases.

CONCLUSIONS: Data from SURTRI study report acceptable 30-day results but significantly reduced late survival in the setting of endocarditis of the tricuspid valve. Multi-disciplinary approach, repair strategy and earlier treatment may improve outcomes.

Original languageEnglish
Pages (from-to)116-120
Number of pages5
JournalInternational Journal of Cardiology
Early online date13 Sept 2022
Publication statusPublished - 15 Jan 2023

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