Prognostic role of endocarditis in isolated tricuspid valve surgery. A propensity-weighted study

Michele Di Mauro; Marco Russo; Guglielmo Saitto; Antonio Lio; Paolo Berretta; Maurizio Taramasso; Roberto Scrofani; Alessandro Della Corte; Sandro Sponga; Ernesto Greco; Matteo Saccocci; Antonio Calafiore; Giacomo Bianchi; Dror B Leviner; Andrea Biondi; Ugolino Livi; Erez Sharoni; Carlo De Vincentiis; Marco Di Eusanio; Carlo Antona; Giovanni Troise; Marco Solinas; Guenther Laufer; Francesco Musumeci; Martin Andreas

doi:10.1016/j.ijcard.2022.09.020

Prognostic role of endocarditis in isolated tricuspid valve surgery. A propensity-weighted study

Michele Di Mauro, Marco Russo^*, Guglielmo Saitto, Antonio Lio, Paolo Berretta, Maurizio Taramasso, Roberto Scrofani, Alessandro Della Corte, Sandro Sponga, Ernesto Greco, Matteo Saccocci, Antonio Calafiore, Giacomo Bianchi, Dror B Leviner, Andrea Biondi, Ugolino Livi, Erez Sharoni, Carlo De Vincentiis, Marco Di Eusanio, Carlo AntonaGiovanni Troise, Marco Solinas, Guenther Laufer, Francesco Musumeci, Martin Andreas

^*Corresponding author for this work

Research output: Contribution to journal › Article › Academic › peer-review

Abstract

OBJECTIVES: The role of the underlying etiology in isolated tricuspid valve surgery has not been investigated extensively in current literature. Aim of this study was to analyse outcomes of patients undergoing surgery due to endocarditis compared to other pathologies.

METHODS: The SURTRI study is a multicenter study enrolling adult patients who underwent isolated tricuspid valve surgery (n = 406, 55 ± 16 y.o.; 56% female) at 13 international sites. Propensity weighted analysis was performed to compare groups (IE group n = 107 vs Not-IE group n = 299).

RESULTS: No difference was found regarding the 30-day mortality (Group IE: 2.8% vs Group Not-IE = 6.8%; OR = 0.45) and major adverse events. Weighted cumulative incidence of cardiac death was significantly higher for patients with endocarditis (p = 0.01). The composite endpoint of cardiac death and reoperation at 6 years was reduced in the Group IE (63.2 ± 6.8% vs 78.9 ± 3.1%; p = 0.022). Repair strategy resulted in an increased late survival even in IE cases.

CONCLUSIONS: Data from SURTRI study report acceptable 30-day results but significantly reduced late survival in the setting of endocarditis of the tricuspid valve. Multi-disciplinary approach, repair strategy and earlier treatment may improve outcomes.

Original language	English
Pages (from-to)	116-120
Number of pages	5
Journal	International Journal of Cardiology
Volume	371
Issue number	1
Early online date	13 Sept 2022
DOIs	https://doi.org/10.1016/j.ijcard.2022.09.020
Publication status	Published - 15 Jan 2023

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Di Mauro, M., Russo, M., Saitto, G., Lio, A., Berretta, P., Taramasso, M., Scrofani, R., Della Corte, A., Sponga, S., Greco, E., Saccocci, M., Calafiore, A., Bianchi, G., Leviner, D. B., Biondi, A., Livi, U., Sharoni, E., De Vincentiis, C., Di Eusanio, M., ... Andreas, M. (2023). Prognostic role of endocarditis in isolated tricuspid valve surgery. A propensity-weighted study. International Journal of Cardiology, 371(1), 116-120. https://doi.org/10.1016/j.ijcard.2022.09.020

@article{8abe8b439b224f5bbc9992b91da22208,

title = "Prognostic role of endocarditis in isolated tricuspid valve surgery. A propensity-weighted study",

abstract = "OBJECTIVES: The role of the underlying etiology in isolated tricuspid valve surgery has not been investigated extensively in current literature. Aim of this study was to analyse outcomes of patients undergoing surgery due to endocarditis compared to other pathologies.METHODS: The SURTRI study is a multicenter study enrolling adult patients who underwent isolated tricuspid valve surgery (n = 406, 55 ± 16 y.o.; 56% female) at 13 international sites. Propensity weighted analysis was performed to compare groups (IE group n = 107 vs Not-IE group n = 299).RESULTS: No difference was found regarding the 30-day mortality (Group IE: 2.8% vs Group Not-IE = 6.8%; OR = 0.45) and major adverse events. Weighted cumulative incidence of cardiac death was significantly higher for patients with endocarditis (p = 0.01). The composite endpoint of cardiac death and reoperation at 6 years was reduced in the Group IE (63.2 ± 6.8% vs 78.9 ± 3.1%; p = 0.022). Repair strategy resulted in an increased late survival even in IE cases.CONCLUSIONS: Data from SURTRI study report acceptable 30-day results but significantly reduced late survival in the setting of endocarditis of the tricuspid valve. Multi-disciplinary approach, repair strategy and earlier treatment may improve outcomes.",

author = "{Di Mauro}, Michele and Marco Russo and Guglielmo Saitto and Antonio Lio and Paolo Berretta and Maurizio Taramasso and Roberto Scrofani and {Della Corte}, Alessandro and Sandro Sponga and Ernesto Greco and Matteo Saccocci and Antonio Calafiore and Giacomo Bianchi and Leviner, {Dror B} and Andrea Biondi and Ugolino Livi and Erez Sharoni and {De Vincentiis}, Carlo and {Di Eusanio}, Marco and Carlo Antona and Giovanni Troise and Marco Solinas and Guenther Laufer and Francesco Musumeci and Martin Andreas",

note = "Copyright {\textcopyright} 2022. Published by Elsevier B.V.",

year = "2023",

month = jan,

day = "15",

doi = "10.1016/j.ijcard.2022.09.020",

language = "English",

volume = "371",

pages = "116--120",

journal = "International Journal of Cardiology",

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Di Mauro, M, Russo, M, Saitto, G, Lio, A, Berretta, P, Taramasso, M, Scrofani, R, Della Corte, A, Sponga, S, Greco, E, Saccocci, M, Calafiore, A, Bianchi, G, Leviner, DB, Biondi, A, Livi, U, Sharoni, E, De Vincentiis, C, Di Eusanio, M, Antona, C, Troise, G, Solinas, M, Laufer, G, Musumeci, F & Andreas, M 2023, 'Prognostic role of endocarditis in isolated tricuspid valve surgery. A propensity-weighted study', International Journal of Cardiology, vol. 371, no. 1, pp. 116-120. https://doi.org/10.1016/j.ijcard.2022.09.020

TY - JOUR

T1 - Prognostic role of endocarditis in isolated tricuspid valve surgery. A propensity-weighted study

AU - Di Mauro, Michele

AU - Russo, Marco

AU - Saitto, Guglielmo

AU - Lio, Antonio

AU - Berretta, Paolo

AU - Taramasso, Maurizio

AU - Scrofani, Roberto

AU - Della Corte, Alessandro

AU - Sponga, Sandro

AU - Greco, Ernesto

AU - Saccocci, Matteo

AU - Calafiore, Antonio

AU - Bianchi, Giacomo

AU - Leviner, Dror B

AU - Biondi, Andrea

AU - Livi, Ugolino

AU - Sharoni, Erez

AU - De Vincentiis, Carlo

AU - Di Eusanio, Marco

AU - Antona, Carlo

AU - Troise, Giovanni

AU - Solinas, Marco

AU - Laufer, Guenther

AU - Musumeci, Francesco

AU - Andreas, Martin

PY - 2023/1/15

Y1 - 2023/1/15

N2 - OBJECTIVES: The role of the underlying etiology in isolated tricuspid valve surgery has not been investigated extensively in current literature. Aim of this study was to analyse outcomes of patients undergoing surgery due to endocarditis compared to other pathologies.METHODS: The SURTRI study is a multicenter study enrolling adult patients who underwent isolated tricuspid valve surgery (n = 406, 55 ± 16 y.o.; 56% female) at 13 international sites. Propensity weighted analysis was performed to compare groups (IE group n = 107 vs Not-IE group n = 299).RESULTS: No difference was found regarding the 30-day mortality (Group IE: 2.8% vs Group Not-IE = 6.8%; OR = 0.45) and major adverse events. Weighted cumulative incidence of cardiac death was significantly higher for patients with endocarditis (p = 0.01). The composite endpoint of cardiac death and reoperation at 6 years was reduced in the Group IE (63.2 ± 6.8% vs 78.9 ± 3.1%; p = 0.022). Repair strategy resulted in an increased late survival even in IE cases.CONCLUSIONS: Data from SURTRI study report acceptable 30-day results but significantly reduced late survival in the setting of endocarditis of the tricuspid valve. Multi-disciplinary approach, repair strategy and earlier treatment may improve outcomes.

AB - OBJECTIVES: The role of the underlying etiology in isolated tricuspid valve surgery has not been investigated extensively in current literature. Aim of this study was to analyse outcomes of patients undergoing surgery due to endocarditis compared to other pathologies.METHODS: The SURTRI study is a multicenter study enrolling adult patients who underwent isolated tricuspid valve surgery (n = 406, 55 ± 16 y.o.; 56% female) at 13 international sites. Propensity weighted analysis was performed to compare groups (IE group n = 107 vs Not-IE group n = 299).RESULTS: No difference was found regarding the 30-day mortality (Group IE: 2.8% vs Group Not-IE = 6.8%; OR = 0.45) and major adverse events. Weighted cumulative incidence of cardiac death was significantly higher for patients with endocarditis (p = 0.01). The composite endpoint of cardiac death and reoperation at 6 years was reduced in the Group IE (63.2 ± 6.8% vs 78.9 ± 3.1%; p = 0.022). Repair strategy resulted in an increased late survival even in IE cases.CONCLUSIONS: Data from SURTRI study report acceptable 30-day results but significantly reduced late survival in the setting of endocarditis of the tricuspid valve. Multi-disciplinary approach, repair strategy and earlier treatment may improve outcomes.

U2 - 10.1016/j.ijcard.2022.09.020

DO - 10.1016/j.ijcard.2022.09.020

M3 - Article

C2 - 36108764

SN - 0167-5273

VL - 371

SP - 116

EP - 120

JO - International Journal of Cardiology

JF - International Journal of Cardiology

IS - 1

ER -