Prognosis of White-Coat and Masked Hypertension International Database of Home Blood Pressure in Relation to Cardiovascular Outcome

George S. Stergiou, Kei Asayama, Lutgarde Thijs, Anastasios Kollias, Teemu J. Niiranen, Atsushi Hozawa, Jose Boggia, Jouni K. Johansson, Takayoshi Ohkubo, Ichiro Tsuji, Antti M. Jula, Yutaka Imai, Jan A. Staessen*

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review


Home blood pressure monitoring is useful in detecting white-coat and masked hypertension and is recommended for patients with suspected or treated hypertension. The prognostic significance of white-coat and masked hypertension detected by home measurement was investigated in 6458 participants from 5 populations enrolled in the International Database of HOme blood pressure in relation to Cardiovascular Outcomes. During a median follow-up of 8.3 years, 714 fatal plus nonfatal cardiovascular events occurred. Among untreated subjects (n=5007), cardiovascular risk was higher in those with white-coat hypertension (adjusted hazard ratio 1.42; 95% CI [1.06-1.91]; P=0.02), masked hypertension (1.55; 95% CI [1.12-2.14]; P
Original languageEnglish
Pages (from-to)675-682
Issue number4
Publication statusPublished - Apr 2014


  • cardiovascular diseases
  • home blood pressure monitoring
  • masked hypertension
  • meta-analysis
  • prognosis
  • white-coat hypertension

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