Probing the Tumor Suppressor Function of BAP1 in CRISPR-Engineered Human Liver Organoids

Benedetta Artegiani, Lisa van Voorthuijsen, Rik G. H. Lindeboom, Danielle Seinstra, Inha Heo, Pablo Tapia, Carmen Lopez-Iglesias, Daniel Postrach, Talya Dayton, Rurika Oka, Huili Hu, Ruben van Boxtel, Johan H. van Es, Johan Offerhaus, Peter J. Peters, Jacco van Rheenen, Michiel Vermeulen, Hans Clevers*

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

Original languageEnglish
Pages (from-to)927-+
Number of pages23
JournalCell Stem Cell
Volume24
Issue number6
DOIs
Publication statusPublished - 6 Jun 2019

Keywords

  • STEM-CELL ORGANOIDS
  • INTRAHEPATIC CHOLANGIOCARCINOMA
  • WHOLE-GENOME
  • MUTATIONS
  • EXPRESSION
  • MODELS
  • FRACTIONATION
  • INFECTION
  • CHROMATIN
  • PROTEINS

Cite this

Artegiani, B., van Voorthuijsen, L., Lindeboom, R. G. H., Seinstra, D., Heo, I., Tapia, P., Lopez-Iglesias, C., Postrach, D., Dayton, T., Oka, R., Hu, H., van Boxtel, R., van Es, J. H., Offerhaus, J., Peters, P. J., van Rheenen, J., Vermeulen, M., & Clevers, H. (2019). Probing the Tumor Suppressor Function of BAP1 in CRISPR-Engineered Human Liver Organoids. Cell Stem Cell, 24(6), 927-+. https://doi.org/10.1016/j.stem.2019.04.017