Pro-neurogenic, Memory-Enhancing and Anti-stress Effects of DF302, a Novel Fluorine Gamma-Carboline Derivative with Multi-target Mechanism of Action

Tatyana Strekalova, Nataliia Bahzenova, Alexander Trofimov, Angelika G. Schmitt-Bohrer, Nataliia Markova, Vladimir Grigoriev, Vladimir Zamoyski, Tatiana Serkova, Olga Redkozubova, Daria Vinogradova, Alexei Umriukhin, Vladimir Fisenko, Christina Lillesaar, Elena Shevtsova, Vladimir Sokolov, Alexey Aksinenko, Klaus-Peter Lesch, Sergey Bachurin*

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

Original languageEnglish
Pages (from-to)335-349
Number of pages15
JournalMolecular Neurobiology
Volume55
Issue number1
DOIs
Publication statusPublished - 1 Jan 2018

Keywords

  • Alzheimer's disease
  • Multi-target mechanisms
  • Hippocampal plasticity
  • AMPA receptor
  • 5-HT6 receptor
  • Stress and depression
  • Aggression
  • STRESS-INDUCED ANHEDONIA
  • ALZHEIMERS-DISEASE
  • MULTIFACTORIAL NATURE
  • TRANSGENIC MICE
  • RECEPTOR ANTAGONISTS
  • NEURITE OUTGROWTH
  • CORTICAL-NEURONS
  • MOUSE MODEL
  • DIMEBON
  • DEPRESSION

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