Primitive reflexes in alzheimer's disease and vascular dementia

Fred W. Vreeling; Peter J. Houx; Jellemer Jolles; Frans R.J. Verhey

doi:10.1177/089198879500800207

Primitive reflexes in alzheimer's disease and vascular dementia

Fred W. Vreeling, Peter J. Houx, Jellemer Jolles, Frans R.J. Verhey

Research output: Contribution to journal › Article › Academic › peer-review

Abstract

Data on the prevalence and clinical value of primitive reflexes (PRs) in dementia are controversial, mainly due to a lack of standardization of the methods by which these signs are elicited and scored. A standardized protocol was used to investigate eight PRs in 20 patients with Alzheimer's disease (AD), 20 patients with vascular dementia (VD), and 20 control subjects for each group. Both patient groups showed considerably more PRs than the control groups. The prevalence of PRs was related to the severity of dementia. No single reflex or combination of PR pathognomonic for dementia could be distinguished. The PR profile of AD and VD patients were similar.

Original language	English
Pages (from-to)	111-117
Number of pages	7
Journal	Journal of Geriatric Psychiatry and Neurology
Volume	8
Issue number	2
DOIs	https://doi.org/10.1177/089198879500800207
Publication status	Published - 1 Jan 1995

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10.1177/089198879500800207

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title = "Primitive reflexes in alzheimer's disease and vascular dementia",

abstract = "Data on the prevalence and clinical value of primitive reflexes (PRs) in dementia are controversial, mainly due to a lack of standardization of the methods by which these signs are elicited and scored. A standardized protocol was used to investigate eight PRs in 20 patients with Alzheimer's disease (AD), 20 patients with vascular dementia (VD), and 20 control subjects for each group. Both patient groups showed considerably more PRs than the control groups. The prevalence of PRs was related to the severity of dementia. No single reflex or combination of PR pathognomonic for dementia could be distinguished. The PR profile of AD and VD patients were similar.",

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