Primary intracranial germ-cell tumors in adults: a practical review

Jacoline E. C. Bromberg*, Brigitta G. Baumert, Filip de Vos, Johanna M. M. Gijtenbeek, Erkan Kurt, Anneke M. Westermann, Pieter Wesseling

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

16 Citations (Web of Science)


Primary intracranial germ-cell tumors are rare tumors primarily of adolescence, and literature on this disease in adults is scarce. The available evidence on intracranial germ-cell tumors is reviewed with a focus on adult patients whenever possible, and used to make suggestions for diagnosis and treatment. Diagnostic and treatment algorithms were developed to provide an evidence-based backbone to base treatment on in adult patients with a (suspected) primary intracranial germ-cell tumor.
Original languageEnglish
Pages (from-to)175-183
JournalJournal of Neuro-Oncology
Issue number2
Publication statusPublished - Jun 2013


  • Germ-cell tumor
  • Germinoma
  • Intracranial
  • Diagnosis
  • Treatment

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