Prevention of diabetes through lifestyle intervention: effects on liver fat and brain

Mathijs Drummen

doi:10.26481/dis.20190124md

Prevention of diabetes through lifestyle intervention: effects on liver fat and brain

Mathijs Drummen

Research output: Thesis › Doctoral Thesis › Internal

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Abstract

With incidents of type 2 diabetes (T2D) on the rise, more research is needed on possible prevention and treatment strategies. The PREVIEW study described in this dissertation is a large-scale, multi-centre study that compared the effects of different lifestyle interventions on the development of diabetes. It also examined the specific effects on fatty liver and brain activity. The PREVIEW intervention helped to reduce both body weight and insulin resistance and resulted in lower fatty liver levels and greater portion control. As a result, it can be concluded that fatty liver and portion control improvements are associated with increased protein intake.

Original language	English
Awarding Institution	Maastricht University
Supervisors/Advisors	Westerterp - Plantenga, Margriet, Supervisor Adam, Tanja, Co-Supervisor Vreugdenhil, Anita, Co-Supervisor
Award date	24 Jan 2019
Place of Publication	Maastricht
Publisher	Gildeprint Drukkerijen
Print ISBNs	9789463234818
DOIs	https://doi.org/10.26481/dis.20190124md
Publication status	Published - 2019

Keywords

Type 2 diabetes
Prevention
Lifestyle intervention
increased protein intake
human research
Fatty liver
brain activity

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10.26481/dis.20190124md

Full TextFinal published version, 4.31 MB
AbstractFinal published version, 174 KB
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Cite this

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abstract = "With incidents of type 2 diabetes (T2D) on the rise, more research is needed on possible prevention and treatment strategies. The PREVIEW study described in this dissertation is a large-scale, multi-centre study that compared the effects of different lifestyle interventions on the development of diabetes. It also examined the specific effects on fatty liver and brain activity. The PREVIEW intervention helped to reduce both body weight and insulin resistance and resulted in lower fatty liver levels and greater portion control. As a result, it can be concluded that fatty liver and portion control improvements are associated with increased protein intake. ",

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KW - Prevention

KW - Lifestyle intervention

KW - increased protein intake

KW - human research

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KW - brain activity

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Prevention of diabetes through lifestyle intervention: effects on liver fat and brain

Abstract

Keywords

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