Prevalentie en uitingsvormen van agressie bij volwassen patiënten met niet-aangeboren hersenletsel: een literatuuroverzicht

Translated title of the contribution: Prevalence and manifestations of aggression in adult patients with acquired brain injury: a review

C.G.J.G. Pouwels*, G. Wolters Grégorio, P.J.J. Spauwen, B.A.A. Bus, I. Winkens, R.W.H.M. Ponds

*Corresponding author for this work

Research output: Contribution to journal(Systematic) Review article


BACKGROUND: Aggression after acquired brain injury has a major impact on daily functioning for the patient, their family, and caregivers.<br/> AIM: To present the prevalence and manifestations of aggression in patients with different types of brain injury.<br/> METHOD: Systematic search of the literature in PubMed, Psycinfo and Embase.<br/> RESULTS: Fourty-one studies were included in which 15 different outcome measures for aggression were used. The prevalence of agitation ranged between 4.0%-93.9% (median 35.8%), of aggression between 3.7%-88.0% (median 35.3%) and of hostility between 4.0%-45.7% (median 9.1%). Prevalence rates were highest in patients with traumatic brain injury. Verbal aggression occurred more frequently (median 33.0%, 14.0%-70.0%) than physical aggression (median 11.5%, 1.5%-33.8%), but manifestations of aggression were only examined in ten studies.<br/> CONCLUSION: Aggression is a common behavioral problem after brain injury. The prevalence varies and depends on the type of brain injury, the specific target behavior and the outcome measure. It is recommended to reach consensus on definitions and outcome measures.

Translated title of the contributionPrevalence and manifestations of aggression in adult patients with acquired brain injury: a review
Original languageDutch
Pages (from-to)862-878
Number of pages17
JournalTijdschrift voor Psychiatrie
Issue number12
Publication statusPublished - 2019


  • Aggression/psychology
  • Brain Injuries/complications
  • Humans
  • Prevalence
  • Problem Behavior
  • Treatment Outcome

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