TY - JOUR
T1 - Prevalence and antibiotic resistance of commensal Streptococcus pneumoniae in nine European countries
AU - Yahiaoui, Rachid Y.
AU - den Heijer, Casper D. J.
AU - van Bijnen, Evelien M. E.
AU - Paget, W. John
AU - Pringle, Mike
AU - Goossens, Herman
AU - Bruggeman, Catharina
AU - Schellevis, Francois G.
AU - Stobberingh, Ellen E.
PY - 2016/6
Y1 - 2016/6
N2 - The human microbiota represents an important reservoir of antibiotic resistance. Moreover, the majority of antibiotics are prescribed in primary care. For this reason, we assessed the prevalence and antibiotic resistance of nasal carriage strains of Streptococcus pneumoniae, the most prevalent bacterial causative agent of community-acquired respiratory tract infections, in outpatients in nine European countries. Nasal swabs were collected between October 2010 and May 2011, from 32,770 patients, recruited by general practices in nine European countries. Overall prevalence of S. pneumoniae nasal carriage in the nine countries was 2.9%. The carriage was higher in men (3.7%) than in women (2.7%). Children (4-9 years) had a higher carriage prevalence (27.2%) compared with those older than 10 years (1.9%). The highest resistance observed was to cefaclor. The highest prevalence of multidrug resistance was found in Spain and the lowest prevalence was observed in Sweden.
AB - The human microbiota represents an important reservoir of antibiotic resistance. Moreover, the majority of antibiotics are prescribed in primary care. For this reason, we assessed the prevalence and antibiotic resistance of nasal carriage strains of Streptococcus pneumoniae, the most prevalent bacterial causative agent of community-acquired respiratory tract infections, in outpatients in nine European countries. Nasal swabs were collected between October 2010 and May 2011, from 32,770 patients, recruited by general practices in nine European countries. Overall prevalence of S. pneumoniae nasal carriage in the nine countries was 2.9%. The carriage was higher in men (3.7%) than in women (2.7%). Children (4-9 years) had a higher carriage prevalence (27.2%) compared with those older than 10 years (1.9%). The highest resistance observed was to cefaclor. The highest prevalence of multidrug resistance was found in Spain and the lowest prevalence was observed in Sweden.
KW - antibiotic resistance
KW - nasal swab
KW - Streptococcus pneumoniae
U2 - 10.2217/fmb-2015-0011
DO - 10.2217/fmb-2015-0011
M3 - Article
C2 - 27191588
SN - 1746-0913
VL - 11
SP - 737
EP - 744
JO - Future Microbiology
JF - Future Microbiology
IS - 6
ER -