Preoperative breast radiation therapy: Indications and perspectives

S. V. Lightowlers*, L. J. Boersma, A. Fourquet, Y. M. Kirova, B. V. Offersen, P. Poortmans, A. N. Scholten, N. Somaiah, C. E. Coles

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

32 Citations (Web of Science)

Abstract

Preoperative breast radiation therapy (RT) is not a new concept, but older studies failed to change practice. More recently, there has been interest in revisiting preoperative RT using modern techniques. This current perspective discusses the indications, summarises the published literature and then highlights current clinical trials, with particular attention to combining with novel drugs and optimising associated translational research. (C) 2017 Elsevier Ltd. All rights reserved.

Original languageEnglish
Pages (from-to)184-192
Number of pages9
JournalEuropean Journal of Cancer
Volume82
DOIs
Publication statusPublished - Sep 2017

Keywords

  • Preoperative breast radiation therapy
  • IMRT
  • Translational research
  • INTENSITY-MODULATED RADIOTHERAPY
  • POSTMASTECTOMY RADIOTHERAPY
  • NEOADJUVANT CHEMOTHERAPY
  • CONCURRENT PACLITAXEL
  • PATHOLOGICAL RESPONSE
  • CLINICAL DEVELOPMENT
  • PHASE-II
  • CANCER
  • TRIAL
  • IRRADIATION

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