Pregnancy outcome after fetal reduction in women with a dichorionic twin pregnancy

L. van de Mheen; S. M. P. Everwijn; M. F. C. M. Knapen; M. C. Haak; M. A. J. Engels; G. T. R. Manten; H. A. Zondervan; S. A. M. Wirjosoekarto; J. M. G. van Vugt; J. J. H. M. Erwich; C. M. Bilardo; M. G. van Pampus; C. J. M. de Groot; B. W. J. Mol; E. Pajkrt

doi:10.1093/humrep/dev132

Pregnancy outcome after fetal reduction in women with a dichorionic twin pregnancy

L. van de Mheen^*, S. M. P. Everwijn, M. F. C. M. Knapen, M. C. Haak, M. A. J. Engels, G. T. R. Manten, H. A. Zondervan, S. A. M. Wirjosoekarto, J. M. G. van Vugt, J. J. H. M. Erwich, C. M. Bilardo, M. G. van Pampus, C. J. M. de Groot, B. W. J. Mol, E. Pajkrt

^*Corresponding author for this work

Research output: Contribution to journal › Article › Academic › peer-review

Abstract

STUDY QUESTION: What are the pregnancy outcomes for women with a twin pregnancy that is reduced to a singleton pregnancy? summary answer: Fetal reduction of a twin pregnancy significantly improves gestational age at birth and neonatal birthweight, however at an increased risk of pregnancy loss and preterm delivery. what is known already: Women with a multiple pregnancy are at increased risk for preterm delivery. Fetal reduction can be considered in these women. study design, size, and duration: Retrospective cohort study of 118 women with a twin pregnancy reduced to a singleton pregnancy between 2000 and 2010. participants/materials, setting, and methods: We compared the outcome of pregnancy in consecutive women with a dichorionic twin pregnancy that was reduced to a singleton pregnancy to that of women with a dichorionic twin pregnancy that was managed expectantly and women with a primary singleton pregnancy. Reductions were performed between 10-23(6/7) weeks' gestation by intracardiac or intrathoracic injection of potassium chloride, mostly for congenital anomalies. We compared median gestational age, pregnancy loss

Original language	English
Pages (from-to)	1807-1812
Journal	Human Reproduction
Volume	30
Issue number	8
DOIs	https://doi.org/10.1093/humrep/dev132
Publication status	Published - Aug 2015

Keywords

twin pregnancy
fetal reduction
congenital abnormality
pregnancy outcome

Access to Document

10.1093/humrep/dev132

Cite this

van de Mheen, L., Everwijn, S. M. P., Knapen, M. F. C. M., Haak, M. C., Engels, M. A. J., Manten, G. T. R., Zondervan, H. A., Wirjosoekarto, S. A. M., van Vugt, J. M. G., Erwich, J. J. H. M., Bilardo, C. M., van Pampus, M. G., de Groot, C. J. M., Mol, B. W. J., & Pajkrt, E. (2015). Pregnancy outcome after fetal reduction in women with a dichorionic twin pregnancy. Human Reproduction, 30(8), 1807-1812. https://doi.org/10.1093/humrep/dev132

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title = "Pregnancy outcome after fetal reduction in women with a dichorionic twin pregnancy",

abstract = "STUDY QUESTION: What are the pregnancy outcomes for women with a twin pregnancy that is reduced to a singleton pregnancy? summary answer: Fetal reduction of a twin pregnancy significantly improves gestational age at birth and neonatal birthweight, however at an increased risk of pregnancy loss and preterm delivery. what is known already: Women with a multiple pregnancy are at increased risk for preterm delivery. Fetal reduction can be considered in these women. study design, size, and duration: Retrospective cohort study of 118 women with a twin pregnancy reduced to a singleton pregnancy between 2000 and 2010. participants/materials, setting, and methods: We compared the outcome of pregnancy in consecutive women with a dichorionic twin pregnancy that was reduced to a singleton pregnancy to that of women with a dichorionic twin pregnancy that was managed expectantly and women with a primary singleton pregnancy. Reductions were performed between 10-23(6/7) weeks' gestation by intracardiac or intrathoracic injection of potassium chloride, mostly for congenital anomalies. We compared median gestational age, pregnancy loss ",

keywords = "twin pregnancy, fetal reduction, congenital abnormality, pregnancy outcome",

author = "{van de Mheen}, L. and Everwijn, {S. M. P.} and Knapen, {M. F. C. M.} and Haak, {M. C.} and Engels, {M. A. J.} and Manten, {G. T. R.} and Zondervan, {H. A.} and Wirjosoekarto, {S. A. M.} and {van Vugt}, {J. M. G.} and Erwich, {J. J. H. M.} and Bilardo, {C. M.} and {van Pampus}, {M. G.} and {de Groot}, {C. J. M.} and Mol, {B. W. J.} and E. Pajkrt",

year = "2015",

month = aug,

doi = "10.1093/humrep/dev132",

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van de Mheen, L, Everwijn, SMP, Knapen, MFCM, Haak, MC, Engels, MAJ, Manten, GTR, Zondervan, HA, Wirjosoekarto, SAM, van Vugt, JMG, Erwich, JJHM, Bilardo, CM, van Pampus, MG, de Groot, CJM, Mol, BWJ & Pajkrt, E 2015, 'Pregnancy outcome after fetal reduction in women with a dichorionic twin pregnancy', Human Reproduction, vol. 30, no. 8, pp. 1807-1812. https://doi.org/10.1093/humrep/dev132

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AU - Knapen, M. F. C. M.

AU - Haak, M. C.

AU - Engels, M. A. J.

AU - Manten, G. T. R.

AU - Zondervan, H. A.

AU - Wirjosoekarto, S. A. M.

AU - van Vugt, J. M. G.

AU - Erwich, J. J. H. M.

AU - Bilardo, C. M.

AU - van Pampus, M. G.

AU - de Groot, C. J. M.

AU - Mol, B. W. J.

AU - Pajkrt, E.

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AB - STUDY QUESTION: What are the pregnancy outcomes for women with a twin pregnancy that is reduced to a singleton pregnancy? summary answer: Fetal reduction of a twin pregnancy significantly improves gestational age at birth and neonatal birthweight, however at an increased risk of pregnancy loss and preterm delivery. what is known already: Women with a multiple pregnancy are at increased risk for preterm delivery. Fetal reduction can be considered in these women. study design, size, and duration: Retrospective cohort study of 118 women with a twin pregnancy reduced to a singleton pregnancy between 2000 and 2010. participants/materials, setting, and methods: We compared the outcome of pregnancy in consecutive women with a dichorionic twin pregnancy that was reduced to a singleton pregnancy to that of women with a dichorionic twin pregnancy that was managed expectantly and women with a primary singleton pregnancy. Reductions were performed between 10-23(6/7) weeks' gestation by intracardiac or intrathoracic injection of potassium chloride, mostly for congenital anomalies. We compared median gestational age, pregnancy loss

KW - twin pregnancy

KW - fetal reduction

KW - congenital abnormality

KW - pregnancy outcome

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DO - 10.1093/humrep/dev132

M3 - Article

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JO - Human Reproduction

JF - Human Reproduction

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