Pregnancy after Hematopoietic Cell Transplantation: A Report from the Late Effects Working Committee of the Center for International Blood and Marrow Transplant Research (CIBMTR)

Alison W. Loren, Eric Chow, David A. Jacobsohn, Maria Gilleece, Joerg Halter, Sarita Joshi, Zhiwei Wang, Kathleen A. Sobocinski, Vikas Gupta, Gregory A. Hale, David I. Marks, Edward A. Stadtmauer, Jane Apperley, Jean-Yves Cahn, Harry C. Schouten, Hillard M. Lazarus, Bipin N. Savani, Philip L. McCarthy, Ann A. Jakubowski, Naynesh R. KamaniBrandon Hayes-Lattin, Richard T. Maziarz, Anne B. Warwick, Mohamed L. Sorror, Brian J. Bolwel, Gerard Socie, John R. Wingard, J. Douglas Rizzo, Navneet S. Majhail*

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

48 Citations (Web of Science)

Abstract

Preservation of fertility after hematopoietic cell transplantation (HCT) can have a significant influence on the quality of life of transplant survivors. We describe 178 pregnancies in HCT recipients that were reported to the Center for International Blood and Marrow Transplant Research (CIBMTR) between 2002 and 2007. There were 83 pregnancies in female HCT recipients and 95 pregnancies in female partners of male HCT recipients. Indications for transplantation included hematologic and other malignancies (N = 99) and nonmalignant disorders (N = 79, of which 75 patients had severe aplastic anemia). The cohort included recipients of autologous HCT (20 women, 13 men), myeloablative (MA) allogeneic HCT (12 women, 50 men), and nonmyeloablative allogeneic HCT (2 women, 2 men). Age at HCT was
Original languageEnglish
Pages (from-to)157-166
JournalBiology of Blood and Marrow Transplantation
Volume17
Issue number2
DOIs
Publication statusPublished - Feb 2011

Keywords

  • Allogeneic hematopoietic cell transplantation
  • Autologous hematopoietic cell transplantation
  • Pregnancy
  • Fertility preservation

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