TY - JOUR
T1 - Predictors of Anticoagulation Use in Indigenous and Non-Indigenous Australians with Atrial Fibrillation
AU - Rocheleau, Simon
AU - Gallagher, Celine
AU - Pitman, Bradley M.
AU - Tu, Samuel J.
AU - Hanna-Rivero, Nicole
AU - Clarke, Nicholas
AU - Linz, Dominik
AU - Hendriks, Jeroen M.
AU - Middeldorp, Melissa E.
AU - Mahajan, Rajiv
AU - Lau, Dennis H.
AU - Roberts-Thomson, Kurt C.
AU - Sanders, Prashanthan
AU - Wong, Christopher X.
N1 - 10.1016/j.hlc.2020.08.027
PY - 2021
Y1 - 2021
N2 - Objective: Prior studies have demonstrated that anticoagulation underutilisation for atrial fibrillation (AF) and elevated stroke risk is common. However, there is little data on factors associated with appropriate anticoagulation, particularly in Indigenous Australians who face a disproportionate burden of AF and stroke. We thus sought to determine factors associated with anticoagulation use in Australians with AF. Design: Administrative, clinical, prescriptive and laboratory data were linked and aggregated over a 12-year period. Setting: Single tertiary teaching hospital. Participants: 19,305 (98%) and 308 (2%) consecutive non-Indigenous and Indigenous Australians with AF identified from administrative databases. Main outcome measures: Associations of anticoagulation use according to ethnicity. Results: Significant independent predictors of anticoagulation use included hypertension (odds ratio [OR] 1.25, 95% confidence interval [CI] 1.17–1.34; p
AB - Objective: Prior studies have demonstrated that anticoagulation underutilisation for atrial fibrillation (AF) and elevated stroke risk is common. However, there is little data on factors associated with appropriate anticoagulation, particularly in Indigenous Australians who face a disproportionate burden of AF and stroke. We thus sought to determine factors associated with anticoagulation use in Australians with AF. Design: Administrative, clinical, prescriptive and laboratory data were linked and aggregated over a 12-year period. Setting: Single tertiary teaching hospital. Participants: 19,305 (98%) and 308 (2%) consecutive non-Indigenous and Indigenous Australians with AF identified from administrative databases. Main outcome measures: Associations of anticoagulation use according to ethnicity. Results: Significant independent predictors of anticoagulation use included hypertension (odds ratio [OR] 1.25, 95% confidence interval [CI] 1.17–1.34; p
KW - Anticoagulation Atrial fibrillation Indigenous Stroke
U2 - 10.1016/j.hlc.2020.08.027
DO - 10.1016/j.hlc.2020.08.027
M3 - Article
SN - 1443-9506
VL - 30
SP - 707
EP - 713
JO - Heart Lung and Circulation
JF - Heart Lung and Circulation
IS - 5
ER -