Prediction of the degree of liver fibrosis using different pattern recognition techniques

Ahmed M. Hashem, M. Emad M. Rasmy, Khaled M. Wahba, Olfat G. Shaker

Research output: Chapter in Book/Report/Conference proceedingConference article in proceedingAcademicpeer-review

Abstract

Liver biopsy is considered as mandatory for the management of patients infected with the hepatitis C virus (HCV), particularly for staging of fibrosis degree. However, due to its invasive nature and limitations of sampling error, the tendency is to substitute the liver biopsy with non-invasive method. The objective of this study is to combine the serum biomarkers and histopathological findings to develop a classification model that can predict the hepatic fibrosis stage. The best developed classification model was able to predict the different fibrosis grades with accuracy of 93.7%. This accuracy represents a substantial improvement over previous works and would pave the way to utilize classification models as a clinically non-invasive and reliable method to assess the degree of liver fibrosis.

Original languageEnglish
Title of host publication2010 5th Cairo International Biomedical Engineering Conference, CIBEC 2010
Pages210-214
Number of pages5
DOIs
Publication statusPublished - 2010
Externally publishedYes
Event2010 5th Cairo International Biomedical Engineering Conference, CIBEC 2010 - Cairo, Egypt
Duration: 16 Dec 201018 Dec 2010

Publication series

SeriesCairo International Biomedical Engineering Conference, CIBEC, Proceedings

Conference

Conference2010 5th Cairo International Biomedical Engineering Conference, CIBEC 2010
Abbreviated titleCIBEC 2010
Country/TerritoryEgypt
CityCairo
Period16/12/1018/12/10

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