Predicted changes in fatty acid intakes, plasma lipids, and cardiovascular disease risk following replacement of trans fatty acid-containing soybean oil with application-appropriate alternatives.

M. Lefevre, R.P. Mensink, P.M. Kris Etherton, B. Petersen, K. Smith, B. D. Flickinger

Research output: Contribution to journalArticleAcademicpeer-review

Abstract

The varied functional requirements satisfied by trans fatty acid (TFA)-containing oils constrains the selection of alternative fats and oils for use as potential replacements in specific food applications. We aimed to model the effects of replacing TFA-containing partially hydrogenated soybean oil (PHSBO) with application-appropriate alternatives on population fatty acid intakes, plasma lipids, and cardiovascular disease (CVD) risk. Using the National Health and Nutrition Examination Survey 24-hour dietary recalls for 1999-2002, we selected 25 food categories, accounting for 86 % of soybean oil (SBO) and 79 % of TFA intake for replacement modeling. Before modeling, those in the middle quintile had a mean PHSBO TFA intake of 1.2 % of energy. PHSBO replacement in applications requiring thermal stability by either low-linolenic acid SBO or mid-oleic, low-linolenic acid SBO decreased TFA intake by 0.3 % of energy and predicted CVD risk by 0.7-0.8 %. PHSBO replacement in applications requiring functional properties with palm-based oils reduced TFA intake by 0.8 % of energy, increased palmitic acid intake by 1.0 % of energy, and reduced predicted CVD risk by 0.4 %, whereas replacement with fully hydrogenated interesterified SBO reduced TFA intake by 0.7 % of energy, increased stearic acid intake by 1.0 % of energy, and decreased predicted CVD risk by 1.2 %. PHSBO replacement in both thermal and functional applications reduced TFA intake by 1.0 % of energy and predicted CVD risk by 1.5 %. Based solely on changes in plasma lipids and lipoproteins, all PHSBO replacement models reduced estimated CVD risk, albeit less than previously reported using simpler replacement models.
Original languageEnglish
Pages (from-to)951-962
Number of pages12
JournalLipids
Volume47
Issue number10
DOIs
Publication statusPublished - Oct 2012

Keywords

  • trans fatty acid
  • Partially hydrogenated soybean oil (PHSBO)
  • Cardiovascular disease
  • Linolenic acid
  • CORONARY-HEART-DISEASE
  • DIETARY-FAT
  • SUBSTITUTION
  • RATIO
  • RICH

Cite this