Predation Stress Causes Excessive Aggression in Female Mice with Partial Genetic Inactivation of Tryptophan Hydroxylase-2: Evidence for Altered Myelination-Related Processes

Evgeniy Svirin, Ekaterina Veniaminova, João Pedro Costa-Nunes, Anna Gorlova, Aleksei Umriukhin, Allan V Kalueff, Andrey Proshin, Daniel C Anthony, Andrey Nedorubov, Anna Chung Kwan Tse, Susanne Walitza, Lee Wei Lim, Klaus-Peter Lesch, Tatyana Strekalova

Research output: Contribution to journalArticleAcademicpeer-review

Original languageEnglish
Article number1036
Number of pages22
JournalCells
Volume11
Issue number6
DOIs
Publication statusPublished - 18 Mar 2022

Keywords

  • Aggression/physiology
  • Animals
  • Female
  • Glycogen Synthase Kinase 3 beta
  • Male
  • Mice
  • Predatory Behavior
  • Rats
  • Serotonin/metabolism
  • Tryptophan Hydroxylase/genetics
  • TRANSCRIPTION FACTOR-1 MYT1
  • female aggression
  • 5-HT receptors
  • glycogen synthase kinase-3 beta (GSK-3 beta)
  • SOCIAL DEFEAT
  • MOUSE MODEL
  • SEROTONIN
  • INDUCED ANHEDONIA
  • HIPPOCAMPAL NEUROGENESIS
  • C57BL/6 MICE
  • PREFRONTAL CORTEX
  • predation stress
  • MATERNAL SEPARATION
  • TREADMILL EXERCISE
  • tryptophan hydroxylase-2 (Tph2)
  • myelination

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